Current Issue February 2012, Vol. 48, No. 3

Issue Highlights

  • Ulceration and stage are predictive of interferon efficacy in melanoma: Results of the phase III adjuvant trials EORTC 18952 and EORTC 18991
    January 2012 (Vol. 48 | No. 2 | Pages 218-225)

    Alexander M.M. Eggermont, Stefan Suciu, Alessandro Testori, Wim H. Kruit, Jeremy Marsden, Cornelis J. Punt, Mario Santinami, François Salès, Dirk Schadendorf, Poulam Patel, Reinhard Dummer, Caroline Robert, Ulrich Keilholz, Antoine Yver, Alan Spatz

  • Targeted agents: How to select the winners in preclinical and early clinical studies?
    January 2012 (Vol. 48 | No. 2 | Pages 170-178)

    Rachel Goodwin, Giuseppe Giaccone, Hilary Calvert, Marinus Lobbezoo, Elizabeth A. Eisenhauer

  • The efficacy of zoledronic acid in breast cancer adjuvant therapy: A meta-analysis of randomised controlled trials
    January 2012 (Vol. 48 | No. 2 | Pages 187-195)

    Tingting Yan, Wenjin Yin, Qiong Zhou, Liheng Zhou, Yiwei Jiang, Yueyao Du, Zhimin Shao, Jinsong Lu

EJC News Focus

The combination of targeted agents in hormone-sensitive breast cancer may be the way ahead; results from the CLEOPATRA and BOLERO-2 trials, presented at the recent San Antonio Breast Cancer Symposium (Dec 6-10, 2011), suggest that some combinations may dramatically increase progression-free survival.

Also at the meeting, several studies reported on the role of bisphosphonates in the adjuvant setting, which may resolve previous confusion about which women will benefit.

In this month's EJC News Focus, Rob Coleman (University of Sheffield, UK), who was at the meeting, discusses the implications of the new data with Helen Saul.

  • Adaptive designs at European Organisation for Research and Treatment of Cancer (EORTC) with a focus on adaptive sample size re-estimation based on interim-effect size
    27 January 2012

    M. Mauer, L. Collette, J. Bogaerts, European Organisation for Research and Treatment of Cancer (EORTC) Statistics Department

  • Inhibition of human hepatocellular carcinoma HepG2 by phthalocyanine photosensitiser ZnPcS2P2: ROS production, apoptosis, cell cycle arrest
    24 January 2012

    Jingwei Shao, Jinping Xue, Yongchao Dai, Hong Liu, Lee Jia, Naisheng Chen, Jinling Huang

  • Quantifying heterogeneity in human tumours using MRI and PET
    24 January 2012

    Marie-Claude Asselin, James P.B. O’Connor, Ronald Boellaard, Neil A. Thacker, Alan Jackson

  • Radiomics: Extracting more information from medical images using advanced feature analysis
    18 January 2012

    Philippe Lambin, Emmanuel Rios-Velazquez, Ralph Leijenaar, Sara Carvalho, Ruud G.P.M. van Stiphout, Patrick Granton, Catharina M.L. Zegers, Robert Gillies, Ronald Boellard, André Dekker, Hugo J.W.L. Aerts

  • The antitumour activities induced by pegylated liposomal cytochalasin D in murine models
    18 January 2012

    Feng-ying Huang, Wen-li Mei, Yue-nan Li, Guang-hong Tan, Hao-fu Dai, Jun-li Guo, Hua Wang, Yong-hao Huang, Huan-ge Zhao, Song-lin Zhou, Ling Li, Ying-ying Lin

  • View More Articles in Press...

On the Cover

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New: Hormone Receptor Positive Breast Cancer Resource Centre

For all the latest research on Hormone Receptor Positive Breast Cancer, including original research articles and video interviews with leading researchers, visit our new resource centre at www.ejcancer-breast.com, edited by Professor Robert E. Coleman.

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About the Journal

European Journal of Cancer is an international comprehensive oncology journal that publishes original research, editorial comments, review articles and news on experimental oncology, clinical oncology (medical, paediatric, radiation, surgical), and on cancer epidemiology and prevention.

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