European Journal of Cancer
Volume 41, Issue 13 , Pages 1911-1922, September 2005

How good are rodent models of carcinogenesis in predicting efficacy in humans? A systematic review and meta-analysis of colon chemoprevention in rats, mice and men

UMR Xenobiotiques, Institut National Recherche Agronomique, Ecole Nationale Veterinaire Toulouse, BP-87614, 23 Capelles, 31076 Toulouse, France

Received 31 March 2005; received in revised form 13 June 2005; accepted 15 June 2005.

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PII: S0959-8049(05)00476-4

doi:10.1016/j.ejca.2005.06.006

European Journal of Cancer
Volume 41, Issue 13 , Pages 1911-1922, September 2005

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