European Journal of Cancer
Volume 42, Issue 15 , Pages 2420-2424 , October 2006

Expression of transcription factor Yin Yang 1 in human osteosarcomas

  • Filomena de Nigris

      Affiliations

    • Department of General Pathology, Division of Clinical Pathology, 1st School of Medicine, II University of Naples, Italy
  • ,
  • Chiara Botti

      Affiliations

    • Department of General Pathology, Division of Clinical Pathology, 1st School of Medicine, II University of Naples, Italy
  • ,
  • Anna de Chiara

      Affiliations

    • National Institute of Tumours, Divisions of Human Pathology and Oncology, Fondazione Pascale, Naples, Italy
  • ,
  • Raffaele Rossiello

      Affiliations

    • Division of Human Pathology, 1st School of Medicine, II University of Naples, Italy
  • ,
  • Gaetano Apice

      Affiliations

    • National Institute of Tumours, Divisions of Human Pathology and Oncology, Fondazione Pascale, Naples, Italy
  • ,
  • Flavio Fazioli

      Affiliations

    • National Institute of Tumours, Divisions of Human Pathology and Oncology, Fondazione Pascale, Naples, Italy
  • ,
  • Carmela Fiorito

      Affiliations

    • Department of General Pathology, Division of Clinical Pathology, 1st School of Medicine, II University of Naples, Italy
  • ,
  • Vincenzo Sica

      Affiliations

    • Department of General Pathology, Division of Clinical Pathology, 1st School of Medicine, II University of Naples, Italy
  • ,
  • Claudio Napoli

      Affiliations

    • Department of General Pathology, Division of Clinical Pathology, 1st School of Medicine, II University of Naples, Italy
    • Corresponding Author InformationCorresponding author: Tel.: +39 081 5665681; fax: +39 081 292399.

Received 18 April 2006 ,Accepted 7 June 2006.

References 

  1. Link MP, Eilber F. Pediatric oncology: osteosarcoma. In:  Pizzo PA,  Poplack DG editor. Principles and practice of pediatric oncology. Philadelphia: Lippincott; 1989;p. 689–711
  2. Weinfeld MS, Dudley HR. Osteogenic sarcoma: a follow-up study of the ninety-four cases observed at the Massachusetts General Hospital from 1920 to 1960. Am J Orthop. 1962;44:269–276
  3. Dahlin DC, Coventry MB. Osteogenic sarcoma. A study of six hundred cases. J Bone Joint Surg Am. 1967;49:101–110
  4. Friedman MA, Carter SK. The therapy of osteogenic sarcoma: current status and thoughts for the future. J Surg Oncol. 1972;4:482–510
  5. Marcove RC, Mike V, Hajek JV. Osteogenic sarcoma under the age of twenty-one. A review of one hundred and forty-five operative cases. J Bone Joint Surg Am. 1970;52:411–423
  6. Fitzgerald RH, Dahlin DC, Sim FH. Multiple metachronous osteogenic sarcoma. Report of twelve cases with two long-term survivors. J Bone Joint Surg Am. 1973;55:595–605
  7. Kaste SC, Pratt CB, Cain AM. Metastases detected at the time of diagnosis of primary pediatric extremity osteosarcoma at diagnosis: imaging features. Cancer. 1999;86:1602–1608
  8. Link MP, Goorin AM, Miser AW. The effect of adjuvant chemotherapy on relapse-free survival in patients with osteosarcoma of the extremity. N Engl J Med. 1986;314:1600–1606
  9. Jeffree GM, Price CH, Sissons HA. The metastatic patterns of osteosarcoma. Br J Cancer. 1975;32:87–107
  10. Rosen G, Forscher CA, Mankin HJ. Neoplasms of bone and soft tissue: bone tumors. In:  Bast RCJ,  Kufe DW,  Pollock RE, et al. editor. Cancer medicine. 5th ed.. Hamilton, Canada: B.C. Decker, Inc.; 2000;p. 1870–1902
  11. Meyers PA, Gorlick R. Osteosarcoma. Pediatr Clin North Am. 1997;44:973–989
  12. Shi Y, Seto E, Chang LS, Shenk T. Transcriptional repression by YY1, a human GLI-Kruppel- related protein, and relief of repression by adenovirus E1A protein. Cell. 1991;67:377–388
  13. Shi Y, Lee JS, Galvin KM. Everything you have ever wanted to know about Yin Yang 1. Biochim Biophys Acta. 1997;1332:F49–F66
  14. Gordon S, Akopyan G, Garban H, Bonavida B. Transcription factor YY1: structure, function, and therapeutic implications in cancer biology. Oncogene. 2006;23:1125–1142
  15. Brankin B, Skaar TC, Brotzman M, Trock B, Clarke R. Autoantibodies to the nuclear phosphoprotein nucleophosmin in breast cancer patients. Cancer Epidemiol Biomarkers Prev. 1998;7:1109–1115
  16. Seligson D, Horvath S, Huerta-Yepez S, et al. Expression of transcription factor Yin Yang 1 in prostate cancer. Int J Oncol. 2005;27:131–141
  17. Vega ML, Jazirchi AR, Huerta-Yepez S, Bonavida B. Rituximab-induced inhibition of YY1 and Bcl-xL expression in Ramos non Hodgkin’s lymphoma cell line via inhibition of NF-KappaB activity: role of YY1 and Bcl-xL in Fas resistance and chemoresistance, respectively. J Immunol. 2005;175:2174–2183
  18. Bain M, Sinclair J. Targeted inhibition of the transcription factor YY1 in an embryonal carcinoma cell line results in retarded cell growth, elevated levels of p53 but no increase in apoptotic cell death. Eur J Cell Biol. 2005;84:543–553
  19. Garban HJ, Bonavida B. Nitric oxide inhibits the transcription repressor Yin-Yang 1 binding activity at the silencer region of the Fas promoter: a pivotal role for nitric oxide in the up-regulation of Fas gene expression in human tumor cells. J Immunol. 2001;167:75–81
  20. Gronroos E, Terentiev AA, Punga T, Ericsson J. YY1 inhibits the activation of the p53 tumor suppressor in response to genotoxic stress. Proc Natl Acad Sci USA. 2004;101:12165–12170
  21. de Nigris F, Youssef T, Ciafre S, et al. Evidence for oxidative activation of c-Myc-dependent nuclear signaling in human coronary smooth muscle cells and in early lesions of Watanabe heritable hyperlipidemic rabbits: protective effects of vitamin E. Circulation. 2000;102:2111–2117
  22. de Nigris F, Crutti J, Morelli C, et al. Isolation of a SI-like gene, Sir-T8, that is overexpressed in thyroid carcinoma cell lines and tissues. Br J Cancer. 2002;86:917–923
  23. Chiappetta G, Tallini G, De Biasio MC, et al. FRA-1 expression in hyperplastic and neoplastic thyroid diseases. Clin Cancer Res. 2000;6:4300–4306
  24. Palko L, Bass HW, Beyrouthy MJ, Hurt MM. The Yin Yang-1 (YY1) protein undergoes a DNA-replication-associated switch in localization from the cytoplasm to the nucleus at the onset of S phase. J Cell Sci. 2004;117:465–476

PII: S0959-8049(06)00554-5

doi: 10.1016/j.ejca.2006.06.008

European Journal of Cancer
Volume 42, Issue 15 , Pages 2420-2424 , October 2006