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European Journal of Cancer
Volume 37, Issue 4
, Pages 503-511
, March 2001
Effects of hexadecylphosphocholine on thrombocytopoiesis
References
- Selective destruction of human leukemic cells by alkyl-lysophospholipids. Cancer Res. 1978;38:3894–3899
- . Selective sensitivity of chronic myelogenous leukemia cell populations to alkyl-lysophospholipids. Blood. 1979;54:519–523
-
.
The influence of alkyl-phospholipids and lysophospholipid-activated macrophages on the development of metastasis of 3 Lewis Lung carcinomas.
Eur. J. Cancer. 1980;16A:1199–1204
- Early tumor and leukemia response to alkyl-lysophospholipids in a phase I study. Cancer. 1982;50:2011–2015
- Cytotoxicity of alkyl-lysophospholipids derivatives and low alkyl-cleavage enzyme activities in rat brain tumor cells. Cancer Res. 1983;43:541–545
- Hexadecylphosphocholine (D18506) in the topical treatment of skin metastases (a phase I trial). Onkologie. 1988;11:295–296
-
.
Hexadecylphosphocholine in the treatment of skin metastasis in breast cancer patients.
Cancer Treatment Rev. 1990;17:243–246
- Phase II trial of orally administered miltefosine in advanced colorectal cancer. Onkologie. 1993;16:11–15
-
.
Phase II study of daily oral hexadecylphosphocholine in advanced colorectal cancer.
Ann. Oncol. 1990;1(Suppl.):46
- Daily oral miltefosine (hexadecylphosphocholine) in patients with advanced non small cell lung cancer. A phase II study. Onkologie. 1992;15:238–242
-
Topical application of hexadecylphosphocholine in patients with cutaneous lymphomas.
In:
Eibl H, Hilgard P, Unger C editor. Progress in Experimental Tumor Research, vol. 24. Alkylphosphocholines: New Drugs in Cancer Therapy. Basel: Karger Verlag; 1992;p. 160–170
- . The induction of apoptosis is a common feature of the cytotoxic action of ether-linked glycerophospholipids in leukemic cells. Int. J. Cancer. 1994;57:645–649
- . Induction of differentiation of cultured mouse myeloid leukemia cells by alkyllysophospholipids. Cancer Res. 1981;41:3211–3216
- . Effects of neoplastic phospholipids on parameters of cell differentiation in U937 cells. J. Cancer Res. Clin. Oncol. 1990;116:459–466
- . Antiinvasive activity of hexadecylphosphocholine in vitro. Anticancer Res. 1991;11:1285–1292
-
.
Hexadecylphosphocholine-mediated enhancement of T-cell responses to interleukin 2.
Cellular Immunol. 1991;137:232–238
-
.
Hexadecylphosphocholine induces interferon-gamma secretion and expression of GM-CSF m RNA in human mononuclear cells.
Cellular Immunol. 1992;141:161–168
- . Disturbance of phospholipid metabolism during selective destruction of tumor cells induced by alkylphospholipids. Cancer Res. 1985;39:4681–4686
- . Effects of hexa-decylphosphocholine on protein kinase C and TPA-induced differentiation of HL 60 cells. Lipids. 1988;26:145–149
- Inhibition of protein kinase C (sodium plus potassium) activated adenosine triphosphatase and sodium pump by synthetic phospholipid analogues. Cancer Res. 1990;50:3025–3031
- . Selective inhibitation of phosphatidylinositol phospholipase C by cytotoxic ether lipid analogues. Cancer Res. 1992;52:2835–2840
- . Hexadecylphosphocholine inhibits phosphatidylinositol and phosphatidylcholine specific phospholipase C in human leukemia cells. J. Exp. Ther. Oncol. 1996;1:302–311
- . Differential regulation of phospholipase A2 in human leukemia cells by the etherphospholipid analogue hexadecylphosphocholine. Biochem. Pharmacol. 1997;53:1725–1733
- . Alkyllysophospholipids activate the SAPK/JNK pathway and enhance radiation-induced apoptosis. Cancer Res. 1999;59:2457–2463
- . Increases in leucocyte and patelet counts induced by the alkyl-phospholipid hexadecylphosphocholine. Eur. J. Cancer. 1994;30A:1019–1022
- . Effects of ether lipids on mouse granulocyte macrophage progenitor cells. Cancer Chemother. Pharmacol. 1989;24:58–60
- . Tumor necrosis factor release by murine macrophages stimulated by the cytotoxic ether lipid 1-O-hexadecyl-2-O-methyl-sn-glycero-3-phosphorylcholine (ET-18-OCH3). Int. J. Immunopharmacol. 1994;16:335–343
- Tumor cytotoxicity of human macrophages after incubation with synthetic analogues of 2-lysophosphatidylcholine. J. Natl. Cancer Inst. 1984;72:53–59
- . Reduction of epidermal growth factor binding in human breast cancer cell lines by an alkyl-lysophospholipid. Cancer Res. 1988;49:2868–2870
- . Different mechanisms of inhibitation by alkyl-lysophospholipid and phorbol ester of granulocyte-macrophage colony stimulating factor binding to human leukemic cell lines. Exp. Hematol. 1994;22:13–18
- . Identification of functional platelet-activating factor receptors in Raji lymphoblasts. J. Immunol. 1989;143:3708–3713
- . Investigations on the cellular uptake of hexadecylphosphocholine. Lipids. 1993;28:731–736
-
.
Hexadecylphosphocholine (oral treatment of visceral leishmaniasis in mice).
Antimicrob. Agents Chemother. 1992;352:1630–1634
- Miltefosine, an oral agent, for the treatment of indian visceral leishmaniasis. N. Engl. J. Med. 1999;341:1795–1800
-
.
Visceral leishmaniasis activity of hexadecylphosphocholine (miltefosine) in mice deficient in T cells and activated macrophage microbicidal mechanisms.
J. Infect. Dis. 2000;181/2:779–795
PII: S0959-8049(00)00394-4
© 2001 Elsevier Science Ltd. All rights reserved.
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European Journal of Cancer
Volume 37, Issue 4
, Pages 503-511
, March 2001
