European Journal of Cancer
Volume 41, Issue 4 , Pages 523-530, March 2005

A Phase I trial of prolonged administration of lovastatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or of the cervix☆

  • Jennifer J. Knox

      Affiliations

    • Departments of Medical Oncology, Princess Margaret Hospital, Ontario Cancer Institute, University Health Network, 5-218, 610 University Avenue, Toronto, Ont., Canada M5G 2M9
    • Corresponding Author InformationCorresponding author. Tel.: 416 946 2399; fax: 416 946 6546
    • ,
  • Lillian L. Siu

      Affiliations

    • Departments of Medical Oncology, Princess Margaret Hospital, Ontario Cancer Institute, University Health Network, 5-218, 610 University Avenue, Toronto, Ont., Canada M5G 2M9
    • ,
  • Eric Chen

      Affiliations

    • Departments of Medical Oncology, Princess Margaret Hospital, Ontario Cancer Institute, University Health Network, 5-218, 610 University Avenue, Toronto, Ont., Canada M5G 2M9
    • ,
  • Jim Dimitroulakos

      Affiliations

    • Cellular and Molecular Biology, Princess Margaret Hospital, Ontario Cancer Institute, University Health Network, Toronto, Canada
    • ,
  • Suzanne Kamel-Reid

      Affiliations

    • Cellular and Molecular Biology, Princess Margaret Hospital, Ontario Cancer Institute, University Health Network, Toronto, Canada
    • ,
  • Malcolm J. Moore

      Affiliations

    • Departments of Medical Oncology, Princess Margaret Hospital, Ontario Cancer Institute, University Health Network, 5-218, 610 University Avenue, Toronto, Ont., Canada M5G 2M9
    • ,
  • Soo Chin

      Affiliations

    • Departments of Medical Oncology, Princess Margaret Hospital, Ontario Cancer Institute, University Health Network, 5-218, 610 University Avenue, Toronto, Ont., Canada M5G 2M9
    • ,
  • Jonathan Irish

      Affiliations

    • Surgical Oncology, Princess Margaret Hospital, Ontario Cancer Institute, University Health Network, Toronto, Canada
    • ,
  • Stephane LaFramboise

      Affiliations

    • Surgical Oncology, Princess Margaret Hospital, Ontario Cancer Institute, University Health Network, Toronto, Canada
    • ,
  • Amit M. Oza

      Affiliations

    • Departments of Medical Oncology, Princess Margaret Hospital, Ontario Cancer Institute, University Health Network, 5-218, 610 University Avenue, Toronto, Ont., Canada M5G 2M9

Received 11 October 2004; received in revised form 10 December 2004; accepted 14 December 2004.

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☆ This manuscript contains original work. The work has been presented in part at the American Association for Cancer Research-National Cancer Institute-European Organisation for Research and Treatment of Cancer (AACR-NCI-EORTC): Molecular Targets and Cancer Therapeutics Meeting, Miami October 2001. A Phase I trial of prolonged administration of lovastatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck (HNSCC) or of the cervix (CC). Abstract #347.

PII: S0959-8049(04)01034-2

doi:10.1016/j.ejca.2004.12.013

European Journal of Cancer
Volume 41, Issue 4 , Pages 523-530, March 2005

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