« Previous
Next »
European Journal of Cancer
Volume 41, Issue 11
, Pages 1515-1527
, July 2005
Essential roles of IGFBP-3 and IGFBP-rP1 in breast cancer
References
- . Insulin-like growth factors and neoplasia. Nat Rev Cancer. 2004;4:505–518
- . Insulin-like growth factors and neoplasia. Novartis Found Symp. 2004;262:84–98discussion 98–107, 265–268
- . The insulin-like growth factor-binding protein (IGFBP) superfamily. Endocr Rev. 1999;20:761–787
- . Structure and function of the insulin-like growth factor I receptor. Breast Cancer Res Treat. 1998;47:235–253
- . Physiological role of the insulin-like growth factor binding proteins. Eur J Endocrinol/Eur Fed Endocr Soc. 1995;132:645–654
- . Growth, differentiation, and survival: multiple physiological functions for insulin-like growth factors. Physiol Rev. 1996;76:1005–1026
- Insulin-like growth factor-binding protein-3 is partially responsible for high-serum-induced apoptosis in PC-3 prostate cancer cells. J Endocrinol. 1999;163:487–494
- . Cellular actions of the insulin-like growth factor binding proteins. Endocr Rev. 2002;23:824–854
- The Twisted gastrulation family of proteins, together with the IGFBP and CCN families, comprise the TIC superfamily of cysteine rich secreted factors. Mol Pathol. 2001;54:317–323
- Evolution of insulin-like growth factor binding proteins. Growth Regul. 1993;3:29–32
- . How many insulin-like growth factor binding proteins?. Mol Cell Endocrinol. 1998;139:1–6
- Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): characterization of connective tissue growth factor as a member of the IGFBP superfamily. Proc Natl Acad Sci USA. 1997;94:12981–12986
- Heparin-binding, highly basic regions within the thyroglobulin type-1 repeat of insulin-like growth factor (IGF)-binding proteins (IGFBPs) -3, -5, and -6 inhibit IGFBP-4 degradation. Endocrinology. 1997;138:2280–2285
- Matrix metalloproteinase-7 facilitates insulin-like growth factor bioavailability through its proteinase activity on insulin-like growth factor binding protein 3. Cancer Res. 2004;64:665–671
- The matrix metalloproteinase-9 regulates the insulin-like growth factor-triggered autocrine response in DU-145 carcinoma cells. J Biol Chem. 1999;274:6935–6945
- Insulin-like growth factor binding protein secretion by breast carcinoma cell lines: correlation with estrogen receptor status. Endocrinology. 1990;127:2679–2686
- . Identification and molecular characterization of insulin-like growth factor binding proteins (IGFBP-1, -2, -3, -4, -5 and -6). Prog Growth Factor Res. 1991;3(4):243–266
- . Insulin-like growth factor binding proteins in the human circulation: a review. Hormone Res. 1994;42:140–144
- Interrelationships between follicle stimulating hormone and the growth hormone – insulin-like growth factor – IGF-binding proteins axes in human granulosa cells in culture. J Endocrinol Invest. 1996;19:35–42
- Regulation of myeloid growth and differentiation by the insulin-like growth factor I receptor. Endocrinology. 1997;138:362–368
- Insulin-like growth factor-binding protein (IGFBP)-3 and IGFBP-5 share a common nuclear transport pathway in T47D human breast carcinoma cells. J Biol Chem. 1998;273:18347–18352
- Nuclear localization of insulin-like growth factor binding protein 3 in a lung cancer cell line. Endocrinology. 1997;138:1767–1770
- Nuclear transport of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in opossum kidney cells. Endocrinology. 1997;138:1763–1766
- . Signalling pathways involved in antiproliferative effects of IGFBP-3: a review. Mol Pathol. 2001;54:145–148
- Nuclear import of insulin-like growth factor-binding protein-3 and -5 is mediated by the importin beta subunit. J Biol Chem. 2000;275:23462–23470
- Direct functional interactions between insulin-like growth factor-binding protein-3 and retinoid X receptor-alpha regulate transcriptional signalling and apoptosis. J Biol Chem. 2000;275:33607–33613
- . IGF-binding proteins mediate TGF-beta1-induced apoptosis in bovine mammary epithelial BME-UV1 cells. Comp Biochem Physiol C Toxicol Pharmacol. 2004;139:65–75
- . Effects of IGF-I and -II, IGF binding protein-3 (IGFBP-3), and transforming growth factor-beta (TGF-beta) on growth and apoptosis of human osteosarcoma Saos-2/B-10 cells: lack of IGF-independent IGFBP-3 effects. Eur J Endocrinol. 2001;145:213–221
- . Interactions of high affinity insulin-like growth factor-binding proteins with the type V transforming growth factor-beta receptor in mink lung epithelial cells. J Biol Chem. 1999;274:6711–6717
- . IGFBP-3 activates TGF-beta receptors and directly inhibits growth in human intestinal smooth muscle cells. Am J Physiol Gastrointest Liver Physiol. 2004;287:G795–G802
- . Demonstration of receptors for insulin-like growth factor binding protein-3 on Hs578T human breast cancer cells. J Biol Chem. 1993;268:26045–26048
- The type V transforming growth factor beta receptor is the putative insulin-like growth factor-binding protein 3 receptor. J Biol Chem. 1997;272:20572–20576
- . Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta1 on programmed cell death through a p53- and IGF-independent mechanism. J Biol Chem. 1997;272:12181–12188
- Characterization of insulin-like growth factor binding protein-3 (IGFBP-3) binding to human breast cancer cells: kinetics of IGFBP-3 binding and identification of receptor binding domain on the IGFBP-3 molecule. Endocrinology. 1999;140:1319–1328
- Insulin-like growth factor-binding protein-3 modulates expression of Bax and Bcl-2 and potentiates p53-independent radiation-induced apoptosis in human breast cancer cells. J Biol Chem. 2000;275:39174–39181
- Matrix metalloproteinase 19 regulates insulin-like growth factor-mediated proliferation, migration, and adhesion in human keratinocytes through proteolysis of insulin-like growth factor binding protein-3. Mol Biol Cell. 2003;14:4569–4580
- Matrix metalloproteinase-7 facilitates insulin-like growth factor bioavailability through its proteinase activity on insulin-like growth factor binding protein 3. Cancer Res. 2004;64:665–671
- ADAM28 is activated by MMP-7 (matrilysin-1) and cleaves insulin-like growth factor binding protein-3. Biochem Biophys Res Commun. 2004;315:79–84
- . Phosphorylation of insulin-like growth factor (IGF) binding protein-3 by breast cancer cell membranes enhances IGF-I binding. Endocrinology. 2003;144:4042–4050
- Phosphorylation of insulin-like growth factor binding protein-3 by deoxyribonucleic acid-dependent protein kinase reduces ligand binding and enhances nuclear accumulation. Endocrinology. 2003;144:1984–1993
- . Characterisation of recombinant glycosylation variants of insulin-like growth factor binding protein-3. J Endocrinol. 1999;160:379–387
- Identification and characterization of genes differentially expressed in meningiomas. Cell Growth Differ. 1993;9:715–722
- Synthesis and characterization of insulin-like growth factor-binding protein (IGFBP)-7. Recombinant human mac25 protein specifically binds IGF-I and -II. J Biol Chem. 1996;271:30322–30325
- Cell adhesion activity of a 30-kDa major secreted protein from human bladder carcinoma cells. Biochem Biophys Res Commun. 1994;198:1046–1053
- Specific accumulation of tumour-derived adhesion factor in tumour blood vessels and in capillary tube-like structures of cultured vascular endothelial cells. Proc Natl Acad Sci USA. 1996;93:8384–8389
- Identification of cell-binding site of angiomodulin (AGM/TAF/Mac25) that interacts with heparan sulfates on cell surface. J Cell Biochem. 1999;75:187–195
- Purification and molecular cloning of prostacyclin-stimulating factor from serum-free conditioned medium of human diploid fibroblast cells. Biochem J. 1994;303(Pt 2):591–598
- Breast cancer genome anatomy: correlation of morphological changes in breast carcinomas with expression of the novel gene product Di12. Oncogene. 1998;16:327–333
- Inhibition of insulin receptor activation by insulin-like growth factor binding proteins. J Biol Chem. 1997;272:30729–30734
- . A secreted tumour-suppressor, mac25, with activin-binding activity. Mol Med. 2000;6:126–135
- . Activins, myostatin and related TGF-beta family members as novel therapeutic targets for endocrine, metabolic and immune disorders. Curr Drug Targets Immune Endocr Metabol Disord. 2004;4:157–166
- Down-regulation of activin, activin receptors, and Smads in high-grade breast cancer. Cancer Res. 2003;63:3783–3790
- Genes expressed in human tumour endothelium. Science. 2000;289:1197–1202
- Matrix metalloproteinases as insulin-like growth factor binding protein-degrading proteinases. Prog Growth Factor Res. 1995;6:255–263
- Proteolytic processing of IGFBP-related protein-1 (TAF/angiomodulin/mac25) modulates its biological activity. Biochem Biophys Res Commun. 2003;310:612–618
- Methylation and downregulated expression of mac25/insulin-like growth factor binding protein-7 is associated with liver tumourigenesis in SV40T/t antigen transgenic mice, screened by restriction landmark genomic scanning for methylation (RLGS-M). Biochem Biophys Res Commun. 2000;267:109–117
- Characterization of the promoter of the murine mac25 gene. Biochem Biophys Res Commun. 2000;279:251–257
- Down-regulation of T1A12/mac25, a novel insulin-like growth factor binding protein related gene, is associated with disease progression in breast carcinomas. Oncogene. 1998;16:2459–2467
- Enhanced expression of an insulin growth factor-like binding protein (mac25) in senescent human mammary epithelial cells and induced expression with retinoic acid. Proc Natl Acad Sci USA. 1995;92:4472–4476
- Characterization of insulin-like growth factor-binding protein-related proteins (IGFBP-rPs) 1, 2, and 3 in human prostate epithelial cells: potential roles for IGFBP-rP1 and 2 in senescence of the prostatic epithelium. Endocrinology. 2000;141:4072–4080
- Generation of anti-insulin-like growth factor-binding protein-related protein 1 (IGFBP-rP1/MAC25) monoclonal antibodies and immunoassay: quantification of IGFBP-rP1 in human serum and distribution in human fluids and tissues. J Clin Endocrinol Metab. 2003;88:3401–3408
- Distribution of IGFBP-rP1 in normal human tissues. J Histochem Cytochem. 2000;48:747–754
- A combined approach for gene discovery identifies insulin-like growth factor-binding protein-related protein 1 as a new gene implicated in human endometrial receptivity. J Clin Endocrinol Metab. 2003;88:1849–1857
- Messenger ribonucleic acids for MAC25 and connective tissue growth factor (CTGF) are inversely regulated during folliculogenesis and early luteogenesis. Endocrinology. 2000;141:2648–2657
- Analysis of gene expression in the bovine corpus luteum through generation and characterisation of 960 ESTs. Biochim Biophys Acta. 2004;1679:10–17
- Decreased expression of mac25 mRNA in uterine leiomyomata compared with adjacent myometrium. Am J Reprod Immunol. 2000;43:53–57
- Development of an insulin-like growth factor binding protein-related protein 1 knockout mouse. Proc Amer Assoc Cancer Res. 2005;46:1080
- . The IGF system and breast cancer. Endocr Relat Cancer. 2001;8:197–209
- . IGF and insulin action in the mammary gland: lessons from transgenic and knockout models. J Mammary Gland Biol Neoplasia. 2000;5:19–30
- Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis. Lancet. 2004;363:1346–1353
- Circulating concentrations of insulin-like growth factor-I and risk of breast cancer. Lancet. 1998;351:1393–1396
- Insulin-like growth factor I (IGF-I), IGF-binding proteins, and breast cancer. Cancer Epidemiol Biomarkers Prev. 2002;11:1566–1573
- . Generation and characterization of an IGFBP-7 antibody: identification of 31kD IGFBP-7 in human biological fluids and Hs578T human breast cancer conditioned media. J Clin Endocrinol Metab. 1997;82:1301–1303
- . Detection of novel genes that are up- (Di12) or down-regulated (T1A12) with disease progression in breast cancer. Eur J Cancer Prev. 1998;7:S29–S35
- Identification of genes differentially expressed in ductal carcinoma in situ and invasive breast tumours. Anticancer Res. 2003;23:2043–2052
- Downregulation of the potential suppressor gene IGFBP-rP1 in human breast cancer is associated with inactivation of the retinoblastoma protein, cyclin E overexpression and increased proliferation in estrogen receptor negative tumours. Oncogene. 2001;20:3497–3505
- Insulin-like growth factor receptor expression and function in human breast cancer. Cancer Res. 1990;50:48–53
- . Targeting the IGF-I receptor: from rags to riches. Eur J Cancer. 2004;40:2013–2015
- . Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development. Dev Biol. 1997;189:33–48
- Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice. J Clin Invest. 1989;84:1418–1423
- Development of resistance to insulin-like growth factor binding protein-3 in transfected T47D breast cancer cells. Biochem Biophys Res Commun. 1998;246:325–329
- Insulin-like growth factor binding protein-3 modulates expression of Bax and Bcl-2 and potentiates p53-independent radiation-induced apoptosis in human breast cancer cells. J Biol Chem. 2000;275:39174–39181
- U.S. patents 5,789,547 (US). Title: Method of producing insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding protein-3 (IGFBP-3) with correct folding and disulfide bonding. August 4, 1998. Assignee: Celtrix Pharmaceuticals, Inc. (US)-5,527,776. Title: Treatment of immunologic and hematologic disorders with IGFBP alone or complexed with IGF. Issued: June 18, 1996. Assignee: Celtrix Pharmaceuticals, Inc. (US).
- Insulin-like growth factor-binding protein 3: single-agent and synergistic effects with paclitaxel in breast tumour models. Eur J Cancer. 2004;0(Suppl 2):84;[Abstract 274]
- Jerome L, Yu Q, Belanger S, et al. Recombinant human insulin-like growth factor binding protein-3 (rhIGFBP-3) as a potential therapeutic agent for the treatment of Herceptin-resistant breast cancer. In: 26th San Antonio breast cancer symposium; 2003 [Abstract # 270].
- The potential utility of recombinant human IGF binding protein-3 (rhIGFBP-3) for the treatment of HER-2-positive breast cancer. Proc Am Assoc Cancer Res. 2004;45:[Abstract # 5334]
- Insulin-like growth factor binding protein-related protein 1 inhibits proliferation of MCF-7 breast cancer cells via a senescence-like mechanism. Cell Growth Differ. 2002;13:205–213
- Over-expression of insulin-like growth factor binding protein-related protein-1 (IGFBP-rP1/mac25) in the M12 prostate cancer cell line alters tumour growth by a delay in G1 and cyclin A associated apoptosis. Oncogene. 2002;21:140–147
- Retinoid-induced growth arrest of breast carcinoma cells involves co-activation of multiple growth-inhibitory genes. Cancer Biol Ther. 2002;1:24–27
- . Cortisol enhances the expression of mac25/insulin-like growth factor-binding protein-related protein-1 in cultured osteoblasts. Endocrinology. 1999;140:228–232
- Long-term effects of fenretinide, a retinoic acid derivative, on the insulin-like growth factor system in women with early breast cancer. Cancer Epidemiol Biomarkers Prev. 2001;10:1047–1053
- Expression of the insulin-like growth factor I receptor and urokinase plasminogen activator in breast cancer is associated with poor survival: potential for intervention with 17-allylamino geldanamycin. Cancer Res. 2004;64:286–291
- Smith V, Sausville EA, Camalier RF, et al. Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) to 17-allylamino-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in melanoma models. Cancer Chemother Pharmacol [in press].
- Transgenic mouse models for studying the functions of insulin-like growth factor-binding proteins. FASEB J. 2000;14:629–640
- . Insights from insulin-like growth factor binding protein transgenic mice. Endocrinology. 2002;143:3711–3714
- . The biology of breast cancer. Hematol Oncol Clin North Am. 1999;13:311–332
PII: S0959-8049(05)00350-3
doi: 10.1016/j.ejca.2005.04.023
© 2005 Elsevier Ltd. All rights reserved.
« Previous
Next »
European Journal of Cancer
Volume 41, Issue 11
, Pages 1515-1527
, July 2005
