European Journal of Cancer
Volume 42, Issue 1 , Pages 55-64 , January 2006

The development of the EORTC QLQ-C15-PAL: A shortened questionnaire for cancer patients in palliative care

  • Mogens Groenvold

      Affiliations

    • Research Unit, Department of Palliative Medicine, Bispebjerg Hospital, 23, Bispebjerg Bakke, DK-2400 Copenhagen NV, Denmark
    • Institute of Public Health, University of Copenhagen, Copenhagen, Denmark
    • Corresponding Author InformationCorresponding author. Tel.: +45 3531 3524; fax: +45 3531 2071.
    • ,
  • Morten Aa. Petersen

      Affiliations

    • Research Unit, Department of Palliative Medicine, Bispebjerg Hospital, 23, Bispebjerg Bakke, DK-2400 Copenhagen NV, Denmark
    • ,
  • Neil K. Aaronson

      Affiliations

    • Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
    • ,
  • Juan I. Arraras

      Affiliations

    • Department of Oncology, Hospital of Navarre, Pamplona, Spain
    • ,
  • Jane M. Blazeby

      Affiliations

    • Clinical Sciences at South Bristol, Bristol, UK
    • Department of Social Medicine, University of Bristol, Bristol, UK
    • ,
  • Andrew Bottomley

      Affiliations

    • Quality of Life Unit, EORTC Data Center, Brussels, Belgium
    • ,
  • Peter M. Fayers

      Affiliations

    • Department of Public Health, Aberdeen University Medical School, Aberdeen, UK
    • Unit of Applied Clinical Research, Norwegian University of Science and Technology, Trondheim, Norway
    • ,
  • Alexander de Graeff

      Affiliations

    • Department of Internal Medicine, University Medical Centre, Utrecht, The Netherlands
    • ,
  • Eva Hammerlid

      Affiliations

    • Department of Otolaryngology Head and Neck Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden
    • ,
  • Stein Kaasa

      Affiliations

    • Unit of Applied Clinical Research, Norwegian University of Science and Technology, Trondheim, Norway
    • ,
  • Mirjam A.G. Sprangers

      Affiliations

    • Department of Medical Psychology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    • ,
  • Jakob B. Bjorner

      Affiliations

    • National Institute of Occupational Health, Copenhagen, Denmark
    • Qualitymetric Incorporated, Lincoln, RI, USA
    • ,
  • for the EORTC Quality of Life Group

Received 15 June 2005 ,Accepted 21 June 2005.

References 

  1. Sepulveda C, Marlin A, Yoshida T, Ullrich A. Palliative Care: the World Health Organization’s global perspective. J Pain Symptom Manage. 2002;24:91–96
  2. Kaasa S, Loge JH. Quality of life in palliative care: principles and practice. Palliat Med. 2003;17:11–20
  3. Ferrell BR. Assessing health-related quality of life at the end of life. In:  Lipscomb J,  Gotay CC,  Snyder C editor. Outcomes assessment in cancer. Cambridge: Cambridge University Press; 2005;p. 264–285
  4. Aaronson NK, Ahmedzai S, Bergman B, Bullinger M, Cull A, et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst. 1993;85:365–376
  5. Cella DF, Tulsky DS, Gray G, Sarafian B, Linn E, et al. The functional assessment of cancer therapy scale: development and validation of the general measure. J Clin Oncol. 1993;11:570–579
  6. Stromgren AS, Goldschmidt D, Groenvold M, Petersen MA, Jensen PT, Pedersen L, et al. Self-assessment in cancer patients referred to palliative care: a study of feasibility and symptom epidemiology. Cancer. 2002;94:512–520
  7. Jordhoy MS, Fayers P, Loge JH, Ahlner-Elmqvist M, Kaasa S. Quality of life in palliative cancer care: results from a cluster randomized trial. J Clin Oncol. 2001;19:3884–3894
  8. Kaasa S, Loge JH. Quality-of-life assessment in palliative care. Lancet Oncol. 2002;3:175–182
  9. Garratt A, Schmidt L, Mackintosh A, Fitzpatrick R. Quality of life measurement: bibliographic study of patient assessed health outcome measures. Br Med J. 2002;324:1417
  10. Ringdal GI, Ringdal K. Testing the EORTC Quality of Life Questionnaire on cancer patients with heterogeneous diagnoses. Qual Life Res. 1993;2:129–140
  11. McLachlan SA, Devins GM, Goodwin PJ. Validation of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (QLQ-C30) as a measure of psychosocial function in breast cancer patients. Eur J Cancer. 1998;34:510–517
  12. Groenvold M, Bjorner JB, Klee MC, Kreiner S. Test for item bias in a quality of life questionnaire. J Clin Epidemiol. 1995;48:805–816
  13. Groenvold M, Klee MC, Sprangers MAG, Aaronson NK. Validation of the EORTC QLQ-C30 quality of life questionnaire through combined qualitative and quantitative assessment of patient-observer agreement. J Clin Epidemiol. 1997;50:441–450
  14. Apolone G, Filiberti A, Cifani S, Ruggiata R, Mosconi P. Evaluation of the EORTC QLQ-C30 questionnaire: a comparison with SF-36 Health Survey in a cohort of Italian long-survival cancer patients. Ann Oncol. 1998;9:549–557
  15. Osoba D, Zee B, Pater J, Warr L, Kaizer L, Latreille J. Psychometric properties and responsiveness of the EORTC Quality of Life Questionnaire (QLQ-C30) in patients with breast, ovarian and lung cancer. Qual Life Res. 1994;3:353–364
  16. Fayers P, Weeden S, Curran D. EORTC QLQ-C30 reference values. Brussels: EORTC; 1998;
  17. Fayers PM, Aaronson N, Bjordal K, Groenvold M, Curran D, et al. The EORTC QLQ-C30 scoring manual. 3rd ed.. Brussels: European Organization for Research and Treatment of Cancer; 2001;
  18. Cull A, Sprangers M, Bjordal K, Aaronson N, West K, Bottomley A. EORTC Quality of Life Group translation procedure. 2nd ed.. Brussels: EORTC Quality of Life Group; 2002;
  19. Petersen MAa, Groenvold M, Bjorner JB, Aaronson NK, Conroy T, et al. Use of differential item functioning analysis to assess the equivalence of translations of a questionnaire. Qual Life Res. 2003;12:373–385
  20. King MT. The interpretation of scores from the EORTC quality of life questionnaire QLQ-C30. Qual Life Res. 1996;5:555–567
  21. Osoba D, Rodrigues G, Myles J, Zee B, Pater J. Interpreting the significance of changes in health-related quality-of-life scores. J Clin Oncol. 1998;16:139–144
  22. Bjorner JB, Petersen MA, Groenvold M, Aaronson N, Ahlner-Elmqvist M, et al. Use of item response theory to develop a shortened version of the EORTC QLQ-C30 emotional functioning scale. Qual Life Res. 2004;13:1683–1697
  23. Petersen MAa, Groenvold M, Aaronson NK, Blazeby JM, Brandberg Y, De Graeff A, et al. Item response theory was used to shorten EORTC QLQ-C30 scales for use in palliative care. J Clin Epidemiol. 2005;58:902–908
  24. Blazeby J, Sprangers M, Cull A, Groenvold M, Bottomley A. EORTC Quality of Life Group guidelines for developing questionnaire modules. 3rd ed.. Brussels: EORTC; 2002;
  25. Sprangers MAG, Cull A, Bjordal K, Groenvold M, Aaronson NK for the EORTC Quality of Life Study Group. The European Organization for Research and Treatment of Cancer approach to quality of life assessment: guidelines for developing questionnaire modules. Qual Life Res. 1993;2:287–295
  26. Efficace F, Bottomley A, Vanvoorden V, Blazeby JM. Methodological issues in assessing health-related quality of life of colorectal cancer patients in randomised controlled trials. Eur J Cancer. 2004;40:187–197
  27. Bottomley A, Efficace F, Thomas R, Vanvoorden V, Ahmedzai SH. Health-related quality of life in non-small-cell lung cancer: methodologic issues in randomized controlled trials. J Clin Oncol. 2003;21:2982–2992
  28. Stromgren AS, Groenvold M, Pedersen L, Olsen AK, Sjogren P. Symptomatology of cancer patients in palliative care: content validation of self-assessment questionnaires against medical records. Eur J Cancer. 2002;38:788–794
  29. Cohen SR, Mount BM, Strobel MG, Bui F. The McGill Quality of Life Questionnaire: a measure of quality of life appropriate for people with advanced disease. A preliminary study of validity and acceptability. Palliat Med. 1995;9:207–219
  30. Hearn J, Higginson IJ. Development and validation of a core outcome measure for palliative care: the palliative care outcome scale. Palliative Care Core Audit Project Advisory Group. Qual Health Care. 1999;8:219–227
  31. Byock IR, Merriman MP. Measuring quality of life for patients with terminal illness: the Missoula-VITAS quality of life index. Palliat Med. 1998;12:231–244
  32. Steinhauser KE, Bosworth HB, Clipp EC, McNeilly M, Christakis NA, et al. Initial assessment of a new instrument to measure quality of life at the end of life. J Palliat Med. 2002;5:829–841

PII: S0959-8049(05)00616-7

doi: 10.1016/j.ejca.2005.06.022

European Journal of Cancer
Volume 42, Issue 1 , Pages 55-64 , January 2006

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