European Journal of Cancer
Volume 41, Issue 18 , Pages 2787-2788 , December 2005

Conservative local treatment versus mastectomy after induction chemotherapy in locally advanced breast cancer: A randomised phase III study (EORTC 10974/22002, LAMANOMA) – Why did this study fail?

  • Marcin Sinacki

      Affiliations

    • Department of Oncology and Radiotherapy, Medical University of Gdansk, ul. Debinki, 7, 80-211 Gdansk, Poland
  • ,
  • Jacek Jassem

      Affiliations

    • Department of Oncology and Radiotherapy, Medical University of Gdansk, ul. Debinki, 7, 80-211 Gdansk, Poland
    • Corresponding Author InformationTel./fax: +48 58 349 22 70.
  • ,
  • Geertjan van Tienhoven

      Affiliations

    • Department of Radiation Oncology, Academic Medical Centre, Meiberggdreef 9, 1105 AZ, Amsterdam, The Netherlands

Received 28 February 2005 ,Accepted 30 June 2005.

References 

  1. De Lena M, Varini M, Zucali R, et al. Multimodal treatment for locally advanced breast cancer: results of chemotherapy-radiotherapy versus chemotherapy-surgery. Cancer Clin Trials. 1981;4:229–236
  2. Perloff M, Lesnick GJ, Korzun A, et al. Combination chemotherapy with mastectomy and radiotherapy for stage III breast carcinoma: a cancer and leukemia group B study. J Clin Oncol. 1988;6:261–269

PII: S0959-8049(05)00794-X

doi: 10.1016/j.ejca.2005.06.027

European Journal of Cancer
Volume 41, Issue 18 , Pages 2787-2788 , December 2005