European Journal of Cancer
Volume 42, Issue 12 , Pages 1881-1888, August 2006

TRF2 inhibition triggers apoptosis and reduces tumourigenicity of human melanoma cells☆

  • Annamaria Biroccio

      Affiliations

    • Experimental Chemotherapy Laboratory, “Experimental Research Centre”, Regina Elena Cancer Institute, Via delle Messi d’Oro 156, Rome 00158, Italy
    • Corresponding Author InformationCorresponding author: Tel.: +39 6 52662569; fax: +39 6 52662592.
    • ,
  • Angela Rizzo

      Affiliations

    • Experimental Chemotherapy Laboratory, “Experimental Research Centre”, Regina Elena Cancer Institute, Via delle Messi d’Oro 156, Rome 00158, Italy
    • ,
  • Raffaella Elli

      Affiliations

    • Cellular Biotechnology and Haematology Department, University “La Sapienza”, Rome, Italy
    • ,
  • Catherine-Elaine Koering

      Affiliations

    • Laboratoire de Biologie Moléculaire de la Cellule de l’Ecole Normale Supérieure, CNRS UMR5161, IFR128, Lyon, France
    • ,
  • Aurélie Belleville

      Affiliations

    • Laboratoire de Biologie Moléculaire de la Cellule de l’Ecole Normale Supérieure, CNRS UMR5161, IFR128, Lyon, France
    • ,
  • Barbara Benassi

      Affiliations

    • Experimental Chemotherapy Laboratory, “Experimental Research Centre”, Regina Elena Cancer Institute, Via delle Messi d’Oro 156, Rome 00158, Italy
    • ,
  • Carlo Leonetti

      Affiliations

    • Experimental Chemotherapy Laboratory, “Experimental Research Centre”, Regina Elena Cancer Institute, Via delle Messi d’Oro 156, Rome 00158, Italy
    • ,
  • Malcolm F.G. Stevens

      Affiliations

    • Center for Biomolecular Sciences, School of Pharmacy, The University of Nottingham, Nottingham, UK
    • ,
  • Maurizio D’Incalci

      Affiliations

    • Department of Oncology, Pharmacological Research Institute “Mario Negri”, Milan, Italy
    • ,
  • Gabriella Zupi

      Affiliations

    • Experimental Chemotherapy Laboratory, “Experimental Research Centre”, Regina Elena Cancer Institute, Via delle Messi d’Oro 156, Rome 00158, Italy
    • ,
  • Eric Gilson

      Affiliations

    • Laboratoire de Biologie Moléculaire de la Cellule de l’Ecole Normale Supérieure, CNRS UMR5161, IFR128, Lyon, France
    • Service “Biologie des Tumeurs Solides – Génomique – Protéomique” Centre Hospitalier Lyon-Sud, France

Received 6 September 2005; received in revised form 23 January 2006; accepted 21 March 2006.

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☆ Grant support: Supported by grants from “Associazione Italiana Ricerca sul Cancro” (A.I.R.C.), “Ministero della Salute”, “CNR-MIUR”, “La Ligue Nationale contre le Cancer” and “Canceropole program EPIMED”. A. Rizzo is recipient of a fellowship from Italian Foundation for Cancer Research (F.I.R.C.).

PII: S0959-8049(06)00333-9

doi:10.1016/j.ejca.2006.03.010

European Journal of Cancer
Volume 42, Issue 12 , Pages 1881-1888, August 2006

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