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European Journal of Cancer
Volume 43, Issue 14
, Pages 2074-2081
, September 2007
Dose finding study of oral PSC 833 combined with weekly intravenous etoposide in children with relapsed or refractory solid tumours
References
- . Multidrug resistance reversal in childhood malignancies – potential for a real step forward?. Eur J Cancer. 1996;32:161–167
- . Multidrug resistance modulation in rhabdomyosarcoma and neuroblastoma cell lines. Int J Oncol. 1998;12:1143–1149
- . Characterization and modulation of drug resistance of human paediatric rhabdomyosarcoma cell lines. Br J Cancer. 2000;83:338–345
- Reversal of multi-drug resistance using Valspodar (PSC-833) and doxorubicin in osteosarcoma. Oncol Rep. 2004;12:1023–1031
- . Clinical trial of continuous infusion verapamil, bolus vinblastine and continuous infusion VP-16 in drug-resistant pediatric tumours. Cancer Res. 1989;49:1063–1066
- . Anaphylactoid reactions in children receiving high-dose intravenous cyclosporine for reversal of tumour resistance: the causative role of improper dissolution of Cremophor EL. J Clin Oncol. 1995;13:2508–2516
- . High-dose cyclosporin with etoposide – toxicity and pharmacokinetic interaction in children with solid tumours. Br J Cancer. 1998;77:2304–2309
- Phase I study of etoposide with SDZ PSC 833 as a modulator of multidrug resistance in patients with cancer. J Clin Oncol. 1996;14:610–618
- Phase I study of mitoxantrone plus etoposide with multidrug blockade by SDZ PSC 833 in relapsed or refractory acute myelogenous leukemia. J Clin Oncol. 1997;15:1796–1802
- Parallel phase I studies of daunorubicin given with cytarabine and etoposide with or without the multidrug resistance modulator PSC 833 in previously untreated patients 60 years of age or older with acute myeloid leukemia: results of cancer and leukemia group B study 9420. J Clin Oncol. 1999;17:2831–2839
- A phase I study of induction chemotherapy for older patients with newly diagnosed acute myeloid leukemia (AML) using mitoxantrone, etoposide and the MDR modulator PSC 833: a southwest oncology group study 9617. Leuk Res. 2000;24:567–574
- Phase I study of paclitaxel in combination with a multidrug resistance modulator PSC 833 (Valspodar), in refractory malignancies. J Clin Oncol. 2000;18:1124–1134
- Immunosuppressive therapy for paediatric transplant patients: pharmacokinetic considerations. Clin Pharmacokinet. 2002;41:115–135
- . Pharmacologic interactions between the resistance-modifying cyclosporine SCZ PSC 833 and etoposide (VP 16-213) and enhance in vivo cytostatic activity and toxicity. Int J Cancer. 1992;51:433–438
- Phase I study of mitoxantrone plus etoposide with multidrug blockade by SDZ PSC 833 in relapsed or refractory acute myelogenous leukaemia. J Clin Oncol. 1997;15:1796–1802
- . Phase II study of rapid scheduled etoposide in paediatric soft tissue sarcomas. Eur J Cancer. 1995;31(5):782–784
- . Pilot study of a rapid etoposide-cisplatin regimen in paediatric soft tissue sarcomas. Eur J Cancer. 1992;28:399–403
- . Cellular localization of the multidrug resistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci USA. 1987;84:7735–7738
- . Modulation of anthracycline accumulation and metabolism in rat hepatocytes in culture by three revertants of multidrug resistance. Cancer Chemother Pharmacol. 1994;35:53–58
- A dose finding and pharmacokinetic study of reversal of multidrugf resistance with SDZ PSC 833 in combination with doxorubicin in patients with solid tumours. Clin Cancer Res. 1997;3:2005–2015
- . Enhanced toxicity of dactinomycin and vincristine by cylosporin given to reverse multidrug resistance. J Clin Oncol. 1994;12:1988–1999
- Rapid up-regulation of MDR1 expression by anthracyclines in a classical multidrug-resistant cell line. Br J Cancer. 1995;71:931–936
- . Induction of MDR1 gene expression by anthracycline analogues in a human drug resistant leukaemia cell line. Br J Cancer. 1999;79:831–837
- The value of the MDR1 reversal agent PSC-833 in addition to daunorubicin and cytarabine in the treatment of elderly patients with previously untreated acute myeloid leukaemia (AML), in relation to MDR1 status at diagnosis. Blood. 2005;106:2646–2654
- Mitoxantrone, etoposide and cytarabine with or without valspodar in patients with relapsed or refractory acute myeloid leukaemia and high-risk myelodysplastic syndrome: a phase III trial (E2995). J Clin Oncol. 2004;22:1078–1086
- Dose escalation studies of cytarabine, daunorubicin, and etoposide with and without multidrug resistance modulation with PSC-833 in untreated adults with acute myeloid leukaemia younger then 60 years: final induction results of Cancer and Leukaemia Group B Study 9621. J Clin Oncol. 2004;22:4290–4301
- A phase I trial of liposomal doxorubicin, paclitaxel and valspodar (PSC-833), an inhibitor of multi-drug resistance. Ann Oncol. 2005;16:1968–1973
- Phase I study of pegylated liposomal doxorubicin and the multidrug-resistance modulator, valspodar. Br J Cancer. 2005;93:46–53
PII: S0959-8049(07)00526-6
doi: 10.1016/j.ejca.2007.07.003
© 2007 Elsevier Ltd. All rights reserved.
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European Journal of Cancer
Volume 43, Issue 14
, Pages 2074-2081
, September 2007
