European Journal of Cancer
Volume 44, Issue 1 , Pages 19-24 , January 2008

Endpoints and other considerations in phase I studies of targeted anticancer therapy: Recommendations from the task force on Methodology for the Development of Innovative Cancer Therapies (MDICT)

  • Christopher M. Booth

      Affiliations

    • National Cancer Institute of Canada Clinical Trials Group, 10 Stuart Street, Kingston, ON, Canada K7L 3N6
    • Research Fellow, NCIC Clinical Trials Group.
    • ,
  • A. Hilary Calvert

      Affiliations

    • Northern Institute for Cancer Research, Medical School, Newcastle upon Tyne, UK
    • ,
  • Giuseppe Giaccone

      Affiliations

    • Medical Oncology Branch, National Cancer Institute, Bethesda, USA
    • ,
  • Marinus W. Lobbezoo

      Affiliations

    • NDDO Research Foundation, Amsterdam, The Netherlands
    • ,
  • Lesley K. Seymour

      Affiliations

    • National Cancer Institute of Canada Clinical Trials Group, 10 Stuart Street, Kingston, ON, Canada K7L 3N6
    • ,
  • Elizabeth A. Eisenhauer

      Affiliations

    • National Cancer Institute of Canada Clinical Trials Group, 10 Stuart Street, Kingston, ON, Canada K7L 3N6
    • Corresponding Author InformationCorresponding author: Tel.: +1 613 533 6430; fax: +1 613 533 2941.
    • ,
  • On behalf of the Task Force on Methodology for the Development of Innovative Cancer Therapies

Received 26 July 2007 ,Accepted 31 July 2007.

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PII: S0959-8049(07)00589-8

doi: 10.1016/j.ejca.2007.07.034

European Journal of Cancer
Volume 44, Issue 1 , Pages 19-24 , January 2008

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