European Journal of Cancer
Volume 46, Issue 3 , Pages 606-615 , February 2010

Self-reported symptoms of faecal incontinence among long-term gynaecological cancer survivors and population-based controls

  • Gail Dunberger

      Affiliations

    • Clinical Cancer Epidemiology, Department of Oncology and Pathology, Karolinska Institutet, SE-171 76 Stockholm, Sweden
    • Corresponding Author InformationCorresponding author: Address: Clinical Cancer Epidemiology, Department of Oncology and Pathology, Karolinska University Hospital, Z5U1, SE-171 76 Stockholm, Sweden. Tel.: +46 8 51772934; fax: +46 8 51779621.
    • ,
  • Helena Lind

      Affiliations

    • Clinical Cancer Epidemiology, Department of Oncology and Pathology, Karolinska Institutet, SE-171 76 Stockholm, Sweden
    • ,
  • Gunnar Steineck

      Affiliations

    • Clinical Cancer Epidemiology, Department of Oncology and Pathology, Karolinska Institutet, SE-171 76 Stockholm, Sweden
    • Clinical Cancer Epidemiology, Sahlgrenska Academy, SE-413 45 Gothenburg, Sweden
    • ,
  • Ann-Charlotte Waldenström

      Affiliations

    • Department of Gynaecological Oncology, Sahlgrenska University Hospital, SE-413 45 Gothenburg, Sweden
    • ,
  • Tommy Nyberg

      Affiliations

    • Clinical Cancer Epidemiology, Department of Oncology and Pathology, Karolinska Institutet, SE-171 76 Stockholm, Sweden
    • ,
  • Massoud al-Abany

      Affiliations

    • Clinical Cancer Epidemiology, Department of Oncology and Pathology, Karolinska Institutet, SE-171 76 Stockholm, Sweden
    • Department of Medical Physics, Karolinska University Hospital, SE-171 76 Stockholm, Sweden
    • ,
  • Ullakarin Nyberg

      Affiliations

    • Department of Clinical Neuroscience, Section of Psychiatry, St. Göran, SE-112 81 Stockholm, Sweden
    • ,
  • Elisabeth Åvall-Lundqvist

      Affiliations

    • Department of Gynaecological Oncology, Karolinska University Hospital, SE-171 76 Stockholm, Sweden

Received 5 August 2009 ,Revised 7 October 2009 ,Accepted 15 October 2009.

References 

  1. Gerda Engholm, Jacques Ferlay, Niels Christensen, et al. NORDCAN: cancer incidence, mortality and prevalence in the Nordic countries, Version 3.4. Association of Nordic Cancer Registries. Danish Cancer Society. <http://www.ancr.nu>; 2009.
  2. Creutzberg CL, van Putten WL, Koper PC, et al. The morbidity of treatment for patients with Stage I endometrial cancer: results from a randomized trial. Int J Radiat Oncol Biol Phys. 2001;51:1246–1255
  3. Geinitz H, Zimmermann FB, Thamm R, et al. Late rectal symptoms and quality of life after conformal radiation therapy for prostate cancer. Radiother Oncol. 2006;79:341–347
  4. Haddock MG, Sloan JA, Bollinger JW, et al. Patient assessment of bowel function during and after pelvic radiotherapy: results of a prospective phase III North Central Cancer Treatment Group clinical trial. J Clin Oncol. 2007;25:1255–1259
  5. Petersen S, Jongen J, Petersen C, Sailer M. Radiation-induced sequelae affecting the continence organ: incidence, pathogenesis, and treatment. Dis Colon Rectum. 2007;50:1466–1474
  6. Yeoh E, Sun WM, Russo A, Ibanez L, Horowitz M. A retrospective study of the effects of pelvic irradiation for gynecological cancer on anorectal function. Int J Radiat Oncol Biol Phys. 1996;35:1003–1010
  7. Rubin P, Constine LS, Fajardo LF, Phillips TL, Wasserman TH RTOG Late Effects Working Group. Overview. Late Effects of Normal Tissues (LENT) scoring system. Int J Radiat Oncol Biol Phys. 1995;31:1041–1042
  8. Mornex F, Pavy JJ, Denekamp J, Bolla M. Scoring system of late effects of radiations on normal tissues: the SOMA-LENT scale. Cancer Radiother. 1997;1:622–668
  9. Pavy JJ, Denekamp J, Letschert J, et al. EORTC Late Effects Working Group Late effects toxicity scoring: the SOMA scale. Radiother Oncol. 1995;35:11–15
  10. Pavy JJ, Denekamp J, Letschert J, et al. EORTC Late Effects Working Group Late Effects toxicity scoring: the SOMA scale. Int J Radiat Oncol Biol Phys. 1995;31:1043–1047
  11. Chassagne D, Sismondi P, Horiot JC, et al. A glossary for reporting complications of treatment in gynecological cancers. Radiother Oncol. 1993;26:195–202
  12. Bergmark K, Åvall-Lundqvist E, Dickman PW, Henningsohn L, Steineck G. Vaginal changes and sexuality in women with a history of cervical cancer. New Engl J Med. 1999;340:1383–1389
  13. Henningsohn L, Wijkström H, Dickman PW, Bergmark K, Steineck G. Distressful symptoms after radical cystectomy with urinary diversion for urinary bladder cancer: a Swedish population-based study. Eur Urol. 2001;40:151–162
  14. Kreicbergs U, Valdimarsdottir U, Onelöv E, Henter JI, Steineck G. Talking about death with children who have severe malignant disease. New Engl J Med. 2004;351:1175–1186
  15. Steineck G, Helgesen F, Adolfsson J, et al. Quality of life after radical prostatectomy or watchful waiting. New Engl J Med. 2002;347:790–796
  16. Steineck G, Hunt H, Adolfsson J. A hierarchical step-model for causation of bias-evaluating cancer treatment with epidemiological methods. Acta Oncol. 2006;45:421–429
  17. Nout RA, Putter H, Jurgenliemk-Schulz IM, et al. Quality of life after pelvic radiotherapy or vaginal brachytherapy for endometrial cancer: first results of the randomized PORTEC-2 trial. J Clin Oncol. 2009;27:3547–3556
  18. Klee M, Thranov I, Machin Prof D. The patients’ perspective on physical symptoms after radiotherapy for cervical cancer. Gynecol Oncol. 2000;76:14–23
  19. Andreyev J. Gastrointestinal symptoms after pelvic radiotherapy: a new understanding to improve management of symptomatic patients. Lancet Oncol. 2007;8:1007–1017
  20. Olopade FA, Norman A, Blake P, et al. A modified Inflammatory Bowel Disease questionnaire and the Vaizey Incontinence questionnaire are simple ways to identify patients with significant gastrointestinal symptoms after pelvic radiotherapy. Br J Cancer. 2005;92:1663–1670
  21. Landefeld CS, Bowers BJ, Feld AD, et al. National Institutes of Health State-of-the-Science conference statement: prevention of fecal and urinary incontinence in adults. Ann Intern Med. 2008;148(6):449–458
  22. al-Abany M, Helgason AR, Cronqvist AK, et al. Toward a definition of a threshold for harmless doses to the anal-sphincter region and the rectum. Int J Radiat Oncol Biol Phys. 2005;61:1035–1044
  23. Fokdal L, Honore H, Hoyer M, von der Maase H. Dose–volume histograms associated to long-term colorectal functions in patients receiving pelvic radiotherapy. Radiother Oncol. 2005;74:203–210
  24. Vordermark D, Schwab M, Ness-Dourdoumas R, et al. Association of anorectal dose-volume histograms and impaired fecal continence after 3D conformal radiotherapy for carcinoma of the prostate. Radiother Oncol. 2003;69:209–214
  25. Andreyev HJ, Vlavianos P, Blake P, et al. Gastrointestinal symptoms after pelvic radiotherapy: role for the gastroenterologist?. Int J Radiat Oncol Biol Phys. 2005;62:1464–1471

PII: S0959-8049(09)00781-3

doi: 10.1016/j.ejca.2009.10.023

European Journal of Cancer
Volume 46, Issue 3 , Pages 606-615 , February 2010

Article Tools

* Image Usage & Resolution