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European Journal of Cancer
Volume 46, Issue 8
, Pages 1413-1420
, May 2010
MC1R variants increase melanoma risk in families with CDKN2A mutations: A meta-analysis
References
- . High- and low-penetrance cutaneous melanoma susceptibility genes. Expert Rev Anticancer Ther. 2006;6:657–670
- High-risk melanoma susceptibility genes and pancreatic cancer, neural system tumors, and uveal melanoma across GenoMEL. Cancer Res. 2006;66:9818–9828
- Lifetime risk of melanoma in CDKN2A mutation carriers in a population-based sample. J Natl Cancer Inst. 2005;97:1507–1515
- Population-based prevalence of CDKN2A and CDK4 mutations in patients with multiple primary melanomas. Genes Chromosomes Cancer. 2008;47:175–184
- Geographical variation in the penetrance of CDKN2A mutations for melanoma. J Natl Cancer Inst. 2002;94:894–903
- . Genotype-phenotype relationships in U.S. melanoma-prone families with CDKN2A and CDK4 mutations. J Natl Cancer Inst. 2000;92:1006–1010
- Influence of genes, nevi, and sun sensitivity on melanoma risk in a family sample unselected by family history and in melanoma-prone families. J Natl Cancer Inst. 2004;96:785–795
- MC1R variants, melanoma and red hair color phenotype: a meta-analysis. Int J Cancer. 2008;122:2753–2760
- . Molecular genetics of human pigmentation diversity. Hum Mol Genet. 2009;18:R9–R17
- Melanocortin 1 receptor (MC1R) gene variants are associated with an increased risk for cutaneous melanoma which is largely independent of skin type and hair color. J Invest Dermatol. 2001;117:294–300
- MC1R, ASIP, and DNA repair in sporadic and familial melanoma in a Mediterranean population. J Natl Cancer Inst. 2005;97:998–1007
- Melanocortin receptor-1 gene polymorphisms and the risk of cutaneous melanoma in a low-risk southern European population. J Invest Dermatol. 2006;126:1842–1849
- MC1R genotype modifies risk of melanoma in families segregating CDKN2A mutations. Am J Hum Genet. 2001;69:765–773
- Melanocortin-1 receptor variant R151C modifies melanoma risk in Dutch families with melanoma. Am J Hum Genet. 2001;69:774–779
- Melanocortin-1 receptor (MC1R) gene variants and dysplastic nevi modify penetrance of CDKN2A mutations in French melanoma-prone pedigrees. Cancer Epidemiol Biomarkers Prev. 2005;14:2384–2390
- Association of MC1R variants and risk of melanoma in melanoma-prone families with CDKN2A mutations. Cancer Epidemiol Biomarkers Prev. 2005;14:2208–2212
- Cutaneous phenotype and MC1R variants as modifying factors for the development of melanoma in CDKN2A G101W mutation carriers from 4 countries. Int J Cancer. 2007;121:825–831
- . Advanced methods in meta-analysis: multivariate approach and meta-regression. Stat Med. 2002;21:589–624
- . Methods for trend estimation from summarized dose–response data, with applications to meta-analysis. Am J Epidemiol. 1992;135:1301–1309
- . Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21:1539–1558
- . Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315:629–634
- MC1R common variants, CDKN2A and their association with melanoma and breast cancer risk. Int J Cancer. 2006;119:2597–2602
- CDKN2A mutations and MC1R variants in Italian patients with single or multiple primary melanoma. Pigment Cell Melanoma Res. 2008;21:700–709
- Protective effect of copy number polymorphism of glutathione S-transferase T1 gene on melanoma risk in presence of CDKN2A mutations, MC1R variants and host-related phenotypes. Fam Cancer. 2009;8:371–377
- Contribution of genetic factors for melanoma susceptibility in sporadic US melanoma patients. Exp Dermatol. 2009;18:485–487
- MC1R variation and melanoma risk in the Swedish population in relation to clinical and pathological parameters. Pigment Cell Melanoma Res. 2009;22:196–204
- CDKN2A and MC1R mutations in patients with sporadic multiple primary melanoma. J Invest Dermatol. 2004;122:1327–1330
- Dermoscopic features of melanomas associated with MC1R variants in Spanish CDKN2A mutation carriers. Br J Dermatol. 2009;160:48–53
- Cutaneous melanoma in childhood and adolescence shows frequent loss of INK4A and gain of KIT. J Invest Dermatol. 2009;129:1759–1768
- CDKN2A and MC1R analysis in amelanotic and pigmented melanoma. Melanoma Res. 2009;19:142–145
- CDKN2A mutations in melanoma families from Uruguay. Br J Dermatol. 2009;161:536–541
- Prevalence of variations in melanoma susceptibility genes among Slovenian melanoma families. BMC Med Genet. 2008;9:86
- . Comprehensive evaluation of allele frequency differences of MC1R variants across populations. Hum Mutat. 2007;28:495–505
- Novel MC1R variants in Ligurian melanoma patients and controls. Hum Mutat. 2004;2:103
- Identification of modifier genes for cutaneous malignant melanoma in melanoma-prone families with and without CDKN2A mutations. Int J Cancer. 2009;125:2912–2917
PII: S0959-8049(10)00048-1
doi: 10.1016/j.ejca.2010.01.027
© 2010 Elsevier Ltd. All rights reserved.
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European Journal of Cancer
Volume 46, Issue 8
, Pages 1413-1420
, May 2010
