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A DNA methylation signature associated with aberrant promoter DNA hypermethylation of DNMT3B in human colorectal cancer

  • Covadonga Huidobro

      Affiliations

    • Cancer Epigenetics Laboratory, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), HUCA, Universidad de Oviedo, Oviedo, Spain
    • ,
  • Rocío G. Urdinguio

      Affiliations

    • Cancer Epigenetics Laboratory, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), HUCA, Universidad de Oviedo, Oviedo, Spain
    • ,
  • Ramón María Rodríguez

      Affiliations

    • Cancer Epigenetics Laboratory, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), HUCA, Universidad de Oviedo, Oviedo, Spain
    • ,
  • Cristina Mangas

      Affiliations

    • Cancer Epigenetics Laboratory, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), HUCA, Universidad de Oviedo, Oviedo, Spain
    • ,
  • Vincenzo Calvanese

      Affiliations

    • Department of Immunology and Oncology, Centro Nacional de Biotecnología/CNB-CSIC, Cantoblanco, Madrid 28049, Spain
    • ,
  • Pablo Martínez-Camblor

      Affiliations

    • Unidad de Apoyo a la Investigación CAIBER, OIB, Oviedo, Spain
    • ,
  • Cecilia Ferrero

      Affiliations

    • Cancer Epigenetics Laboratory, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), HUCA, Universidad de Oviedo, Oviedo, Spain
    • ,
  • Adolfo Parra-Blanco

      Affiliations

    • Gastroenterology Department, HUCA, Oviedo, Spain
    • ,
  • Luis Rodrigo

      Affiliations

    • Gastroenterology Department, HUCA, Oviedo, Spain
    • ,
  • Álvaro J. Obaya

      Affiliations

    • Department of Functional Biology, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Oviedo University, Oviedo, Spain
    • ,
  • Laura Suárez-Fernández

      Affiliations

    • Banco de Tumores. Instituto Universitario de Oncología del Principado de Asturias (IUOPA), HUCA, Universidad de Oviedo, 33006 Oviedo, Spain
    • ,
  • Aurora Astudillo

      Affiliations

    • Banco de Tumores. Instituto Universitario de Oncología del Principado de Asturias (IUOPA), HUCA, Universidad de Oviedo, 33006 Oviedo, Spain
    • ,
  • Henar Hernando

      Affiliations

    • Chromatin and Disease Group, Cancer Epigenetics and Biology Programme (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), 08907 L’Hospitalet de Llobregat, Barcelona, Spain
    • ,
  • Esteban Ballestar

      Affiliations

    • Chromatin and Disease Group, Cancer Epigenetics and Biology Programme (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), 08907 L’Hospitalet de Llobregat, Barcelona, Spain
    • ,
  • Agustín F. Fernández

      Affiliations

    • Cancer Epigenetics Laboratory, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), HUCA, Universidad de Oviedo, Oviedo, Spain
    • Corresponding Author InformationCorresponding authors: Address: Department of Immunology and Oncology, Centro Nacional de Biotecnología/CNB-CSIC, Cantoblanco, Madrid 28049, Spain. Tel.: +34 985109475; fax: +34 985109495 (M.F. Fraga).
    • ,
  • Mario F. Fraga

      Affiliations

    • Cancer Epigenetics Laboratory, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), HUCA, Universidad de Oviedo, Oviedo, Spain
    • Department of Immunology and Oncology, Centro Nacional de Biotecnología/CNB-CSIC, Cantoblanco, Madrid 28049, Spain
    • Corresponding Author InformationCorresponding authors: Address: Department of Immunology and Oncology, Centro Nacional de Biotecnología/CNB-CSIC, Cantoblanco, Madrid 28049, Spain. Tel.: +34 985109475; fax: +34 985109495 (M.F. Fraga).

Published online 16 January 2012 Corrected Proof

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PII: S0959-8049(11)01068-9

doi: 10.1016/j.ejca.2011.12.019

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