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Editorial board
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Editorial board
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page ii
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EJC News
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News
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pages 2335-2339
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| Current perspective |
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Continuing medical education in Europe: Towards a harmonised system
09 July 2010
Abstract: One of the first reports on the state of medical education was published in 1910 in North America, with the support of the Carnegie Foundation, showing that the interest for this issue dates...
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A. Costa,
F. Van Hemelryck,
A. Aparicio,
W. Gatzemeier,
J.W. Leer,
B. Maillet,
D.K. Hossfeld
et al.
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Full-length article
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pages 2340-2343
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| Position paper |
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Quality indicators in breast cancer care
02 August 2010
Abstract: To define a set of quality indicators that should be routinely measured and evaluated to confirm that the clinical outcome reaches the requested standards, Eusoma has organised a workshop du...
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M. Rosselli Del Turco,
A. Ponti,
U. Bick,
L. Biganzoli,
G. Cserni,
B. Cutuli,
T. Decker,
M. Dietel,
O. Gentilini,
T. Kuehn,
M.P. Mano,
P. Mantellini,
L. Marotti,
P. Poortmans,
F. Rank,
H. Roe,
E. Scaffidi,
J.A. van der Hage,
G. Viale,
C. Wells,
M. Welnicka-Jaskiewicz,
Y. Wengstöm,
L. Cataliotti
et al.
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Full-length article
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pages 2344-2356
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| Reviews |
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The emerging pathogenic and therapeutic importance of the anaplastic lymphoma kinase gene
07 May 2010
Abstract: The anaplastic lymphoma kinase gene (ALK) is a gene on chromosome 2p23 that has expression restricted to the brain, testis and small intestine but is not expressed in normal lymphoid tissue....
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Fergal C. Kelleher,
Ray McDermott
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Full-length article
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pages 2357-2368
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Metformin: Taking away the candy for cancer?
26 July 2010
Abstract: Metformin is widely used in the treatment of diabetes mellitus type 2 where it reduces insulin resistance and diabetes-related morbidity and mortality. Population-based studies show that met...
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Mathilde Jalving,
Jourik A. Gietema,
Joop D. Lefrandt,
Steven de Jong,
Anna K.L. Reyners,
Rijk O.B. Gans,
Elisabeth G.E. de Vries
et al.
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Full-length article
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pages 2369-2380
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| Clinical oncology |
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Patients report improvements in continuity of care when quality of life assessments are used routinely in oncology practice: Secondary outcomes of a randomised controlled trial
31 May 2010
Abstract: Introduction and aim: In a randomised trial investigating the effects of regular use of health-related quality of life (HRQOL) in oncology practice, we previously reported an improvement in ...
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Galina Velikova,
Ada Keding,
Clare Harley,
Kim Cocks,
Laura Booth,
Adam B. Smith,
Penny Wright,
Peter J. Selby,
Julia M. Brown
et al.
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Full-length article
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pages 2381-2388
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Trends in G-CSF use in 990 patients after EORTC and ASCO guidelines
07 June 2010
Abstract: Background: Although international guidelines have standardised conditions for G-CSF administration, real practice seems to vary. Patients and methods: A large survey was undertaken in Franc...
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C. Falandry,
M. Campone,
G. Cartron,
D. Guerin,
G. Freyer
et al.
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Full-length article
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pages 2389-2398
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Lobular invasive carcinoma of the breast is a molecular entity distinct from luminal invasive ductal carcinoma
23 June 2010
Abstract: In order to get insight into the molecular alterations of invasive lobular carcinoma (ILC), comparative genomic hybridisation array and transcriptomic analyses of a series of 62 oestrogens-p...
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Nadège Gruel,
Carlo Lucchesi,
Virginie Raynal,
Manuel J. Rodrigues,
Gaëlle Pierron,
Rémi Goudefroye,
Paul Cottu,
Fabien Reyal,
Xavier Sastre-Garau,
Alain Fourquet,
Olivier Delattre,
Anne Vincent-Salomon
et al.
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Full-length article
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pages 2399-2407
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The unclear zone in phase II clinical trials
28 June 2010
Abstract: Objective: There appears to be considerable confusion about the interpretation of phase II clinical trial conclusions as contrasted with the alternative (HA) and null (H0) hypotheses. This s...
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Sabrina Allegro,
Gregory R. Pond,
Sébastien J. Hotte
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Full-length article
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pages 2408-2413
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EORTC Melanoma Group sentinel node protocol identifies high rate of submicrometastases according to Rotterdam Criteria
12 July 2010
Abstract: Sentinel node (SN) status is the most important prognostic factor for disease-free survival (DFS) and overall survival (OS) in stages I–II melanoma. We evaluated the positive sentinel node i...
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Augustinus P.T. van der Ploeg,
Alexander C.J. van Akkooi,
Paul I.M. Schmitz,
Senada Koljenovic,
Cornelis Verhoef,
Alexander M.M. Eggermont
et al.
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Full-length article
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pages 2414-2421
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Sequential adjuvant chemotherapy and radiotherapy in endometrial cancer –Results from two randomised studies
09 July 2010
Abstract: Introduction: Endometrial cancer patients with high grade tumours, deep myometrial invasion or advanced stage disease have a poor prognosis. Randomised studies have demonstrated the preventi...
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Thomas Hogberg,
Mauro Signorelli,
Carlos Freire de Oliveira,
Roldano Fossati,
Andrea Alberto Lissoni,
Bengt Sorbe,
Håkan Andersson,
Seija Grenman,
Caroline Lundgren,
Per Rosenberg,
Karin Boman,
Bengt Tholander,
Giovanni Scambia,
Nicholas Reed,
Gennaro Cormio,
Germana Tognon,
Jackie Clarke,
Tomasz Sawicki,
Paolo Zola,
Gunnar Kristensen
et al.
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Full-length article
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pages 2422-2431
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Long-term safety of sorafenib in advanced renal cell carcinoma: Follow-up of patients from phase III TARGET
26 July 2010
Abstract: Background: The phase III Treatment Approaches in Renal cancer Global Evaluation Trial (TARGET) indicated that sorafenib is effective and well tolerated in advanced renal cell carcinoma pati...
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Thomas E. Hutson,
Joaquim Bellmunt,
Camillo Porta,
Cezary Szczylik,
Michael Staehler,
Andrea Nadel,
Sibyl Anderson,
Ronald Bukowski,
Tim Eisen,
Bernard Escudier,
For the Sorafenib TARGET Clinical Trial Group
et al.
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Full-length article
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pages 2432-2440
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| Paediatric oncology |
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Hospitalisations 1998–2000 in a British Columbia population-based cohort of young cancer survivors: Report of the Childhood/Adolescent/Young Adult Cancer Survivors (CAYACS) Research Program
07 June 2010
Abstract: Background and objectives: Because of late effects among survivors of cancer in young people, increased hospitalisations would be expected. This study determined the occurrence, frequency an...
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Nicole M.E. Bradley,
Maria F. Lorenzi,
Zenaida Abanto,
Sam Sheps,
Anne Marie Broemeling,
John J. Spinelli,
Karen Goddard,
Sheila Pritchard,
Paul Rogers,
Mary L. McBride,
for the CAYACS Research Group
et al.
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Full-length article
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pages 2441-2448
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Soft tissue sarcomas in the first year of life
10 June 2010
Abstract: Background: Soft tissue sarcomas (STS) occurring in the first year of life represent a rare entity. Challenges in delivering optimal therapy may affect the outcome in this very young populat...
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Iyad Sultan,
Michela Casanova,
Usama Al-Jumaily,
Cristina Meazza,
Carlos Rodriguez-Galindo,
Andrea Ferrari
et al.
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Full-length article
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pages 2449-2456
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| Epidemiology and cancer prevention |
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Polymorphisms in the adenomatous polyposis coli (APC) gene and advanced colorectal adenoma risk
01 June 2010
Abstract: While germline mutations in the adenomatous polyposis coli (APC) gene cause the hereditary colon cancer syndrome (familial adenomatous polyposis (FAP)), the role of common germline APC varia...
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Hui-Lee Wong,
Ulrike Peters,
Richard B. Hayes,
Wen-Yi Huang,
Arthur Schatzkin,
Robert S. Bresalier,
Ellen M. Velie,
Lawrence C. Brody
et al.
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Full-length article
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pages 2457-2466
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High-ceiling diuretics are associated with an increased risk of basal cell carcinoma in a population-based follow-up study
04 June 2010
Abstract: Introduction: In Caucasians, basal cell carcinoma (BCC) is among the most frequently diagnosed cancers and its incidence is increasing. Known risk factors for the development of BCC are age,...
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Rikje Ruiter,
Loes E. Visser,
Mark Eijgelsheim,
Eline M. Rodenburg,
Albert Hofman,
Jan-Willem W. Coebergh,
Tamar Nijsten,
Bruno H.Ch. Stricker
et al.
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Full-length article
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pages 2467-2472
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Male predominance of upper gastrointestinal adenocarcinoma cannot be explained by differences in tobacco smoking in men versus women
04 June 2010
Abstract: Background: Adenocarcinomas of the upper gastrointestinal tract (UGI) show remarkable male predominance. As smoking is a well-established risk factor, we investigated the role of tobacco smo...
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N.D. Freedman,
M.H. Derakhshan,
C.C. Abnet,
A. Schatzkin,
A.R. Hollenbeck,
K.E.L. McColl
et al.
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Full-length article
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pages 2473-2478
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| Experimental oncology/Translational research |
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ERCC2 Lys751Gln polymorphism is associated with lung cancer among Caucasians
04 June 2010
Abstract: To derive a more precise estimation of the relationship between the excision repair cross-complementing rodent repair deficiency, group 2 (ERCC2) Lys751Gln polymorphism and lung cancer risk,...
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Jian Zhang,
Shi-Yang Gu,
Ping Zhang,
Zhen Jia,
Jian-Hua Chang
et al.
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Full-length article
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pages 2479-2484
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Inhibin-alpha, -betaA and -betaB subunits in uterine non-endometrioid carcinomas: Prognostic significance and clinical implications
05 July 2010
Abstract: Inhibins, dimeric peptide hormones composed of an alpha-subunit and one of two possible beta-subunits (betaA or betaB), exhibit substantial roles in human reproduction and in endocrine-respo...
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Ioannis Mylonas
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Full-length article
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pages 2485-2493
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Aven blocks DNA damage-induced apoptosis by stabilising Bcl-xL
09 July 2010
Abstract: Induction of apoptosis by DNA-damaging agents involves the activation of mitochondrial apoptotic pathway. Aven has been identified as an antiapoptotic protein and has been shown to activate ...
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Ozgur Kutuk,
Sehime Gulsun Temel,
Sahsine Tolunay,
Huveyda Basaga
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Full-length article
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pages 2494-2505
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Prognostic impact of CD31-positive microvessel density in follicular lymphoma patients treated with immunochemotherapy
14 July 2010
Abstract: Background: Tumour-infiltrating mast cells (MCs) can remodel tumour microenvironment and growth by suppressing immune responses and potentiating angiogenesis. Furthermore, accumulation of MC...
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Minna Taskinen,
Esa Jantunen,
Veli-Matti Kosma,
Petri Bono,
Marja-Liisa Karjalainen-Lindsberg,
Sirpa Leppä
et al.
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Full-length article
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pages 2506-2512
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Therapeutic effects and prognostic factors in high-intensity focused ultrasound combined with chemoembolisation for larger hepatocellular carcinoma
21 July 2010
Abstract: The purpose of this study is to evaluate high-intensity focused ultrasound (HIFU) ablation combined with transcatheter arterial chemoembolisation (TACE) in the treatment of larger hepatocell...
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Chuanxing Li,
Weidong Zhang,
Rong Zhang,
Liang Zhang,
Peihong Wu,
Fujun Zhang
et al.
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Full-length article
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pages 2513-2521
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Calendar
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Calendar
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page I
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