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Article Title |
Author(s) |
Type (Status) |
Available Online |
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Four and a half LIM protein 2 (FHL2) negatively regulates the transcription of E-cadherin through interaction with Snail1
DOI: 10.1016/j.ejca.2010.07.045
Abstract: E-cadherin is a hallmark of epithelial–mesenchymal transition (EMT), which plays a crucial role in cancer metastasis. We previously demonstrated that four and a half LIM protein 2 (FHL2) inh...
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Wenjing Zhang,
Jide Wang,
Bing Zou,
Claude Sardet,
Jianming Li,
Colin S.C. Lam,
Lui Ng,
Roberta Pang,
Ivan F.N. Hung,
Victoria P.Y. Tan,
Bo Jiang,
Benjamin C.Y. Wong
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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01 September 2010 |
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Expression of matrix metalloproteinase 9 (MMP-9) and tissue inhibitor of metalloproteinases 1 (TIMP-1) by colorectal cancer cells and adjacent stroma cells – Associations with histopathology and patients outcome
DOI: 10.1016/j.ejca.2010.07.046
Abstract: Aim: To elucidate cellular features accountable for colorectal cancers’ (CRC) capability to invade normal tissue and to metastasize, we investigated the level of the collagenase matrix metal...
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Søren Astrup Jensen,
Ben Vainer,
Annette Bartels,
Nils Brünner,
Jens Benn Sørensen
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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01 September 2010 |
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Downregulation of miR-21 modulates Ras expression to promote apoptosis and suppress invasion of Laryngeal squamous cell carcinoma
DOI: 10.1016/j.ejca.2010.07.047
Abstract: MiRNAs are small, noncoding RNA molecules that emerge as important regulators of cancer-related processes. The miR-21 microRNA is overexpressed in a wide variety of cancers and has been caus...
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Jingyuan Ren,
Dan Zhu,
Ming Liu,
Yanan Sun,
Linli Tian
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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01 September 2010 |
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Interleukin-1β regulates the migratory potential of MDAMB231 breast cancer cells through the hypoxia-inducible factor-1α
DOI: 10.1016/j.ejca.2010.07.044
Abstract: The casual relationship between inflammation and tumour progression has been widely accepted and the etiology of breast cancer has been associated with inflammatory processes. Interleukin (I...
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Antonella Naldini,
Irene Filippi,
Diego Miglietta,
Michele Moschetta,
Raffaella Giavazzi,
Fabio Carraro
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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30 August 2010 |
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Early cessation of the clinical development of LiPlaCis, a liposomal cisplatin formulation
DOI: 10.1016/j.ejca.2010.07.015
Abstract: Purpose: To evaluate the safety and tolerability of LiPlaCis, a liposomal formulated platinum compound, in patients with solid tumours and to determine the maximum tolerated dose (MTD) of in...
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Maja J.A. de Jonge,
Marije Slingerland,
Walter J. Loos,
Erik A.C. Wiemer,
Herman Burger,
Ron H.J. Mathijssen,
Judith R. Kroep,
Margret A.G. den Hollander,
Diane van der Biessen,
Mei-Ho Lam,
Jaap Verweij,
Hans Gelderblom
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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30 August 2010 |
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A phase 2 study of vatalanib in metastatic melanoma patients
DOI: 10.1016/j.ejca.2010.07.014
Abstract: Background: A phase 2 study of vatalanib (PTK787/ZK222584) an oral tyrosine kinase inhibitor of VEGFR 1, 2 and 3 was undertaken in patients with metastatic melanoma. Methods: Adults with pat...
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Natalie Cook,
Bristi Basu,
Swethajit Biswas,
Paula Kareclas,
Colette Mann,
Cheryl Palmer,
Anne Thomas,
Steve Nicholson,
Bruno Morgan,
David Lomas,
Bhawna Sirohi,
Adrian P. Mander,
Mark Middleton,
Pippa G. Corrie
et al.
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European Journal of Cancer
Short communication
(In Press Corrected Proof)
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27 August 2010 |
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An international multicentre validation study of a pain classification system for cancer patients
DOI: 10.1016/j.ejca.2010.07.019
Pain is a key symptom at all stages of cancer. It may be the first sign experienced by the patients, it may be a sign of relapse after curative treatment and many patients with metastatic disease may ...
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Stein Kaasa
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European Journal of Cancer
Discussion
(In Press Corrected Proof)
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27 August 2010 |
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The tumour-targeting human L19-IL2 immunocytokine: Preclinical safety studies, phase I clinical trial in patients with solid tumours and expansion into patients with advanced renal cell carcinoma
DOI: 10.1016/j.ejca.2010.07.033
Abstract: Background: L19-IL2, a tumour-targeting immunocytokine composed of the recombinant human antibody fragment L19 (specific to the alternatively-spliced EDB domain of fibronectin, a well charac...
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Manfred Johannsen,
Gianluca Spitaleri,
Giuseppe Curigliano,
Jan Roigas,
Steffen Weikert,
Carsten Kempkensteffen,
Andreas Roemer,
Christian Kloeters,
Patrik Rogalla,
Gabriele Pecher,
Kurt Miller,
Alexander Berndt,
Hartwig Kosmehl,
Eveline Trachsel,
Manuela Kaspar,
Valeria Lovato,
Reinerio González-Iglesias,
Leonardo Giovannoni,
Hans D. Menssen,
Dario Neri,
Filippo de Braud
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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27 August 2010 |
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First-line therapy with moderate dose capecitabine in metastatic breast cancer is safe and active: Results of the MONICA trial
DOI: 10.1016/j.ejca.2010.07.009
Abstract: Background: To determine activity and safety of capecitabine at a moderate dose of 2000mg/m2 as first-line therapy for metastatic breast cancer. Methods: In this prospective phase II trial, ...
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M. Kaufmann,
N. Maass,
S.D. Costa,
A. Schneeweiß,
S. Loibl,
M.W. Sütterlin,
I. Schrader,
B. Gerber,
W. Bauer,
W. Wiest,
O. Tomé,
A. Distelrath,
V. Hagen,
A. Kleine-Tebbe,
E. Ruckhaeberle,
K. Mehta,
G. von Minckwitz,
for the GBG-39 trialists
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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27 August 2010 |
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Psychological consequences of lymphoedema associated with breast cancer: A prospective cohort study
DOI: 10.1016/j.ejca.2010.07.041
Abstract: Background: The aim of this prospective cohort study of women attending a rehabilitation course at the Dallund Rehabilitation Centre was to explore the emotional and psychological aspects of...
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Ditte Vassard,
Maja Halgren Olsen,
Line Zinckernagel,
Jette Vibe-Petersen,
Susanne Oksbjerg Dalton,
Christoffer Johansen
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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27 August 2010 |
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Human glioblastoma tumours and neural cancer stem cells express the chemokine CX3CL1 and its receptor CX3CR1
DOI: 10.1016/j.ejca.2010.07.022
Abstract: Human gliomas represent an unmet clinical challenge as nearly two-thirds of them are highly malignant lesions with fast progression, resistance to treatment and poor prognosis. The most seve...
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Marco Erreni,
Graziella Solinas,
Paola Brescia,
Daniela Osti,
Federica Zunino,
Piergiuseppe Colombo,
Annarita Destro,
Massimo Roncalli,
Alberto Mantovani,
Riccardo Draghi,
Daniel Levi,
Riccardo Rodriguez y Baena,
Paolo Gaetani,
Giuliana Pelicci,
Paola Allavena
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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23 August 2010 |
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Bevacizumab/docetaxel association is more efficient than docetaxel alone in reducing breast and prostate cancer cell growth: A new paradigm for understanding the therapeutic effect of combined treatment
DOI: 10.1016/j.ejca.2010.07.021
Abstract: Bevacizumab (Bvz), a Vascular Endothelial Growth Factor (VEGF)-targeted humanised monoclonal antibody, provides clinical benefit in combination with docetaxel (DXL), a microtubule-stabilisin...
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Cécile Ortholan,
Jérôme Durivault,
Jean-Michel Hannoun-Levi,
Mélanie Guyot,
Christine Bourcier,
Damien Ambrosetti,
Stephen Safe,
Gilles Pagès
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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23 August 2010 |
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Toll-like receptor (TLR) 7 and TLR8 expression on CD133+ cells in colorectal cancer points to a specific role for inflammation-induced TLRs in tumourigenesis and tumour progression
DOI: 10.1016/j.ejca.2010.07.017
Abstract: Toll-like receptor (TLR) stimulation results in activation of NF-κB, a key modulator in driving inflammation to cancer and mitogen-activated protein kinases that have been shown to recruit m...
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Martin Grimm,
Mia Kim,
Andreas Rosenwald,
Uwe Heemann,
Christoph-Thomas Germer,
Ana Maria Waaga-Gasser,
Martin Gasser
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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23 August 2010 |
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Optimising methods for communicating survival data to patients undergoing cancer surgery
DOI: 10.1016/j.ejca.2010.07.030
Abstract: Background: Patients undergoing cancer surgery require outcome data to inform decisions, but communication of numerical risk is difficult. This study assessed patient understanding of surviv...
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C.R. Davis,
A.G.K. McNair,
A. Brigic,
M.G. Clarke,
S.T. Brookes,
M.G. Thomas,
J.M. Blazeby
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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23 August 2010 |
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C-reactive protein-associated genetic variants and cancer risk: Findings from FINRISK 1992, FINRISK 1997 and Health 2000 studies
DOI: 10.1016/j.ejca.2010.07.032
Abstract: Background: Evidence from prospective observational studies suggests that elevated circulating C-reactive protein (CRP) concentrations are associated with cancer risk, but it is unclear whet...
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Katriina Heikkilä,
Kaisa Silander,
Veikko Salomaa,
Pekka Jousilahti,
Seppo Koskinen,
Eero Pukkala,
Markus Perola
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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20 August 2010 |
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Amplification of thymidylate synthetase in metastatic colorectal cancer patients pretreated with 5-fluorouracil-based chemotherapy
DOI: 10.1016/j.ejca.2010.07.011
Abstract: Resistance to 5-fluorouracil (5-FU) represents a major contributor to cancer-related mortality in advanced colorectal cancer patients. Genetic variations and expression alterations in genes ...
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Roshawn G. Watson,
Filipe Muhale,
Leigh B. Thorne,
Jinsheng Yu,
Bert H. O’Neil,
Janelle M. Hoskins,
Michael O. Meyers,
Allison M. Deal,
Joseph G. Ibrahim,
Michael L. Hudson,
Christine M. Walko,
Howard L. McLeod,
James T. Auman
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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20 August 2010 |
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Consulting and prescribing behaviour for anxiety and depression in long-term survivors of cancer in the UK
DOI: 10.1016/j.ejca.2010.07.035
Abstract: Introduction: Cancer survivors may experience long-term depression or anxiety, however, there is little previous research on the use of services in this area. We explored consultation and pr...
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Nada F. Khan,
Alison M. Ward,
Eila Watson,
Peter W. Rose
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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20 August 2010 |
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The addition of pravastatin to chemotherapy in advanced gastric carcinoma: A randomised phase II trial
DOI: 10.1016/j.ejca.2010.07.036
Abstract: Purpose: Statins have for long been considered to play a potential role in anticancer treatment based upon their ability to inhibit the mevalonate synthesis pathway. This randomised phase II...
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Inge R.H.M. Konings,
A. van der Gaast,
Lidemarie J. van der Wijk,
Felix E. de Jongh,
Ferry A.L.M. Eskens,
Stefan Sleijfer
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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20 August 2010 |
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Elevated expression of HMGB1 in squamous-cell carcinoma of the head and neck and its clinical significance
DOI: 10.1016/j.ejca.2010.07.016
Abstract: Purpose: HMGB1 overexpression has been reported in a variety of human cancers. However, the role of HMGB1 in squamous-cell carcinoma of the head and neck (SCCHN) remains unclear. The aim of ...
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Yong Liu,
Congliang Xie,
Xin Zhang,
Donghai Huang,
Xiaojuan Zhou,
Pingqing Tan,
Lin Qi,
Guoqing Hu,
Yongquan Tian,
Yuanzheng Qiu
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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19 August 2010 |
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A lethal combination for cancer cells: Synthetic lethality screenings for drug discovery
DOI: 10.1016/j.ejca.2010.07.031
Abstract: In recent years, cancer drug discovery has faced the challenging task of integrating the huge amount of information coming from the genomic studies with the need of developing highly selecti...
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Elisa Ferrari,
Chiara Lucca,
Marco Foiani
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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19 August 2010 |
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Time until definitive quality of life score deterioration as a means of longitudinal analysis for treatment trials in patients with metastatic pancreatic adenocarcinoma
DOI: 10.1016/j.ejca.2010.07.023
Abstract: Background: The Fédération Francophone de Cancérologie Digestive phase III trial in patients with metastatic pancreatic adenocarcinoma comparing 5FU, folinic acid and cisplatin combination f...
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Franck Bonnetain,
Laetitia Dahan,
Emilie Maillard,
Marc Ychou,
Emmanuel Mitry,
Pascal Hammel,
Jean-Louis Legoux,
Philippe Rougier,
Laurent Bedenne,
Jean-François Seitz
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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19 August 2010 |
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Differential expression and prognostic value of HMGA1 in pancreatic head and periampullary cancer
DOI: 10.1016/j.ejca.2010.07.024
Abstract: The high mortality rate and minimal progress made in the treatment of pancreatic cancer over the last few decades, warrant an alternative approach. Treatment protocols should be individualis...
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Jill A. van der Zee,
Timo L.M. ten Hagen,
Wim C.J. Hop,
Herman van Dekken,
Bilyana M. Dicheva,
Ann L.B. Seynhaeve,
Gerben A. Koning,
Alexander M.M. Eggermont,
Casper H.J. van Eijck
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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19 August 2010 |
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Nuclear S100A4 is a novel prognostic marker in colorectal cancer
DOI: 10.1016/j.ejca.2010.07.013
Abstract: Current staging classifications in colorectal cancer are not able to accurately predict patient outcome, and the need for novel prognostic markers is evident. S100A4 is a Ca2+-binding protei...
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Kjetil Boye,
Jahn M. Nesland,
Berit Sandstad,
Gunhild M. Mælandsmo,
Kjersti Flatmark
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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18 August 2010 |
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Detection of extra-axillary lymph node involvement with FDG PET/CT in patients with stage II–III breast cancer
DOI: 10.1016/j.ejca.2010.07.034
Abstract: Purpose: The aim of this prospective study was to assess the incidence of extra-axillary lymph node involvement on baseline FDG PET/CT in patients with stage II–III breast cancer scheduled f...
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Tjeerd S. Aukema,
Marieke E. Straver,
Marie-Jeanne T.F.D. Vrancken Peeters,
Nicola S. Russell,
Kenneth G.A. Gilhuijs,
Wouter V. Vogel,
Emiel J.T. Rutgers,
Renato A. Valdés Olmos
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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18 August 2010 |
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Carbonic anhydrase 9 in clear cell renal cell carcinoma: A marker for diagnosis, prognosis and treatment
DOI: 10.1016/j.ejca.2010.07.020
Abstract: Carbonic anhydrase 9 (CA9) is a transmembrane member of the carbonic anhydrase family. It catalyses the reversible hydration of carbon dioxide into bicarbonate and a proton, thus enabling tu...
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Jacques Tostain,
Guorong Li,
Anne Gentil-Perret,
Marc Gigante
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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16 August 2010 |
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Elevated LDH predicts poor outcome of recurrent germ cell tumours treated with dose dense chemotherapy
DOI: 10.1016/j.ejca.2010.07.004
Abstract: Aims of the study: Prognostic factors for recurrent germ cell tumours (GCTs) treated with dose dense salvage chemotherapy have not been identified. This study determines whether lactate dehy...
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Marco Gerlinger,
Peter Wilson,
Thomas Powles,
Jonathan Shamash
|
European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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16 August 2010 |
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Phase II study of NGR-hTNF, a selective vascular targeting agent, in patients with metastatic colorectal cancer after failure of standard therapy
DOI: 10.1016/j.ejca.2010.07.012
Abstract: Background: NGR-hTNF consists of human tumour necrosis factor (hTNF) fused with the tumour-homing peptide Asp-Gly-Arg (NGR), which is able to selectively bind an aminopeptidase N overexpress...
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Armando Santoro,
Lorenza Rimassa,
Alberto F. Sobrero,
Giovanni Citterio,
Francesco Sclafani,
Carlo Carnaghi,
Anna Pessino,
Francesco Caprioni,
Valeria Andretta,
Maria Chiara Tronconi,
Giovanna Finocchiaro,
Gloria Rossoni,
Angela Zanoni,
Chiara Miggiano,
Gian-Paolo Rizzardi,
Catia Traversari,
Federico Caligaris-Cappio,
Antonio Lambiase,
Claudio Bordignon
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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16 August 2010 |
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A phase I and biology study of gefitinib and radiation in children with newly diagnosed brain stem gliomas or supratentorial malignant gliomas
DOI: 10.1016/j.ejca.2010.07.005
Abstract: Purpose: To estimate the maximum-tolerated dose (MTD); study the pharmacology of escalating doses of gefitinib combined with radiation therapy in patients ⩽21 years with newly diagnosed intr...
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J. Russell Geyer,
Clinton F. Stewart,
Mehmet Kocak,
Alberto Broniscer,
Peter Phillips,
James G. Douglas,
Susan M. Blaney,
Roger J. Packer,
Sri Gururangan,
Anu Banerjee,
Mark W. Kieran,
Larry E. Kun,
Richard J. Gilbertson,
James M. Boyett
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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16 August 2010 |
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Expression of nuclear FIH independently predicts overall survival of clear cell renal cell carcinoma patients
DOI: 10.1016/j.ejca.2010.07.018
Abstract: Aim: The hypoxia inducible factor (HIF) pathway plays an important role in sporadic clear cell renal cell carcinoma (ccRCC) by stimulating processes of angiogenesis, cell proliferation, cell...
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Stephanie G.C. Kroeze,
Joost S. Vermaat,
Aram van Brussel,
Harm H.E. van Melick,
Emile E. Voest,
Trudy G.N. Jonges,
Paul J. van Diest,
John Hinrichs,
J.L.H. Ruud Bosch,
Judith J.M. Jans
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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16 August 2010 |
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Molecular targets of apigenin in colorectal cancer cells: Involvement of p21, NAG-1 and p53
DOI: 10.1016/j.ejca.2010.07.007
Abstract: Persuasive epidemiological and experimental evidence suggests that dietary flavonoids have anti-cancer activity. Since conventional therapeutic and surgical approaches have not been able to ...
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Yi Zhong,
Chutwadee Krisanapun,
Seong-Ho Lee,
Thararat Nualsanit,
Carl Sams,
Penchom Peungvicha,
Seung Joon Baek
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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16 August 2010 |
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STAT3 activation induced by Epstein-Barr virus latent membrane protein1 causes vascular endothelial growth factor expression and cellular invasiveness via JAK3 And ERK signaling
DOI: 10.1016/j.ejca.2010.07.008
Abstract: The principal Epstein–Barr virus (EBV) oncoprotein, latent membrane protein 1 (LMP1), has been suggested to contribute to the highly invasive nature of nasopharyngeal carcinoma (NPC). Signal...
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Zhenlian Wang,
Feijun Luo,
Lili Li,
Lifang Yang,
Duosha Hu,
Xiaoqian Ma,
Zhongxin Lu,
Lunquan Sun,
Ya Cao
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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16 August 2010 |
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The relationship between new-onset diabetes mellitus and pancreatic cancer risk: A case–control study
DOI: 10.1016/j.ejca.2010.07.010
Abstract: Diabetes mellitus (DM) is widely considered to be associated with pancreatic cancer, however, whether DM is a cause or consequence of pancreatic cancer is controversial. In the present study...
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Qiwen Ben,
Quancai Cai,
Zhaoshen Li,
Yaozong Yuan,
Xiaoyan Ning,
Shangxin Deng,
Kaixuan Wang
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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16 August 2010 |
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Receptor tyrosine kinase and downstream signalling analysis in diffuse malignant peritoneal mesothelioma
DOI: 10.1016/j.ejca.2010.06.130
Abstract: Our aim was to assess the activation profile of EGFR, PDGFRB and PDGFRA receptor tyrosine kinases (RTK) and their downstream effectors in a series of cryopreserved diffuse malignant peritone...
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Federica Perrone,
Genny Jocollè,
Marzia Pennati,
Marcello Deraco,
Dario Baratti,
Silvia Brich,
Marta Orsenigo,
Eva Tarantino,
Cinzia De Marco,
Claudia Bertan,
Antonello Cabras,
Rossella Bertulli,
Marco Alessandro Pierotti,
Nadia Zaffaroni,
Silvana Pilotti
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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09 August 2010 |
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Association between Epstein–Barr virus infection and risk for development of pregnancy-associated breast cancer: Joint effect with vitamin D?
DOI: 10.1016/j.ejca.2010.07.006
Abstract: Background: Few studies have evaluated the role of the ubiquitous Epstein–Barr virus (EBV) infection, together with levels of the immunomodulator, vitamin D, in different breast cancer entit...
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Calypse B. Agborsangaya,
Tuula Lehtinen,
Adetunji T. Toriola,
Eero Pukkala,
Helja-Marja Surcel,
Rosamaria Tedeschi,
Matti Lehtinen
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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06 August 2010 |
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Dose-escalation models for combination phase I trials in oncology
DOI: 10.1016/j.ejca.2010.07.002
Abstract: Designing combination drug phase I trials has become increasingly complex, due to the increasing diversity in classes of agents, mechanisms of action, safety profiles and drug-administration...
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Paul Hamberg,
Mark J. Ratain,
Emmanuel Lesaffre,
Jaap Verweij
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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06 August 2010 |
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Interconversion of three measures of performance status: An empirical analysis
DOI: 10.1016/j.ejca.2010.06.126
Abstract: Purpose: To construct empirically a conversion table to convert performance status scores among the Eastern Cooperative Oncology Group (ECOG), Karnofsky Performance Status (KPS) and Palliati...
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Clement Ma,
Shazeen Bandukwala,
Debika Burman,
John Bryson,
Dori Seccareccia,
Subrata Banerjee,
Jeff Myers,
Gary Rodin,
Deborah Dudgeon,
Camilla Zimmermann
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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02 August 2010 |
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Predictors of outcome and methodological issues in children with acute lymphoblastic leukaemia in El Salvador
DOI: 10.1016/j.ejca.2010.07.001
Abstract: Background: Most children with cancer live in low-income countries (LICs) where risk factors in paediatric acute lymphoblastic leukaemia (ALL) developed in high-income countries may not appl...
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Miguel Bonilla,
Sumit Gupta,
Roberto Vasquez,
Soad L. Fuentes,
Gladis deReyes,
Raul Ribeiro,
Lillian Sung
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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02 August 2010 |
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An international validation study of the EORTC QLQ-INFO25 questionnaire: An instrument to assess the information given to cancer patients
DOI: 10.1016/j.ejca.2010.06.118
Abstract: Aim: The EORTC Quality of Life (QOL) Group has developed an instrument to evaluate the information received by cancer patients. This study assessed the psychometric characteristics of the EO...
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Juan Ignacio Arraras,
Eva Greimel,
Orhan Sezer,
Wei-Chu Chie,
Mia Bergenmar,
Anna Costantini,
Teresa Young,
Karin Kuljanic Vlasic,
Galina Velikova
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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02 August 2010 |
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Paclitaxel/carboplatin versus topotecan/paclitaxel/carboplatin in patients with FIGO suboptimally resected stage III–IV epithelial ovarian cancer a multicenter, randomized study
DOI: 10.1016/j.ejca.2010.06.124
Abstract: Objective: The objective of this prospective randomized phase III trial was to compare paclitaxel plus carboplatin (PC) versus topotecan plus carboplatin and paclitaxel (TPC) in women with s...
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Giorgio Bolis,
Giovanna Scarfone,
Francesco Raspagliesi,
Giorgia Mangili,
Saverio Danese,
Paolo Scollo,
Domenica Lo Russo,
Antonella Villa,
Paola Daniela Aimone,
Giovanni Scambia
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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30 July 2010 |
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A study of the pattern of hospital admissions in a specialist Phase I oncology trials unit: Unplanned admissions as an early indicator of patient attrition
DOI: 10.1016/j.ejca.2010.06.123
Abstract: Background: Unplanned hospital admissions (UHAs) in the context of oncology Phase I trials are important, yet rarely reported. Methods: All patients admitted to the Royal Marsden Hospital Ph...
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Andre T. Brunetto,
Joo Ern Ang,
David Olmos,
Daniel Tan,
Jorge Barriuso,
Hendrik-Tobias Arkenau,
Timothy A. Yap,
L. Rhoda Molife,
Udai Banerji,
Johann de Bono,
Ian Judson,
Stan Kaye
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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28 July 2010 |
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Clustering of concordant and discordant cancer types in Swedish couples is rare
DOI: 10.1016/j.ejca.2010.06.125
Abstract: Background: Spouses are exposed to common environmental cancer risk factors during adulthood. Investigating the aggregation of cancer in couples might provide valuable insights into cancer d...
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Marianne Weires,
Justo Lorenzo Bermejo,
Jan Sundquist,
Kari Hemminki
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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26 July 2010 |
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A multi-centre Canadian pilot study of metronomic temozolomide combined with radiotherapy for newly diagnosed paediatric brainstem glioma
DOI: 10.1016/j.ejca.2010.06.115
Abstract: Purpose: Survival rates for paediatric diffuse intrinsic brainstem glioma (DIBSG) are dismal. Metronomic dosing of temozolomide (TMZ) combined with standard radiotherapy may improve survival...
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Julia R. Sharp,
Eric Bouffet,
Diana Stempak,
Janet Gammon,
Derek Stephens,
Donna L. Johnston,
David Eisenstat,
Juliette Hukin,
Yvan Samson,
Ute Bartels,
Uri Tabori,
Annie Huang,
Sylvain Baruchel
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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26 July 2010 |
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MicroRNA-193b regulates proliferation, migration and invasion in human hepatocellular carcinoma cells
DOI: 10.1016/j.ejca.2010.06.127
Abstract: Background and Aims: Recently, some miRNAs have been reported to be connected closely with the development of human hepatocellular carcinoma. However, the functions of these miRNAs in HCC re...
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Chengwang Xu,
Shanshan Liu,
Hanjiang Fu,
Shuai Li,
Yi Tie,
Jie Zhu,
Ruiyun Xing,
Yinghua Jin,
Zhixian Sun,
Xiaofei Zheng
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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26 July 2010 |
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Novel mechanism of reducing tumourigenesis: Upregulation of the DNA repair enzyme OGG1 by rapamycin-mediated AMPK activation and mTOR inhibition
DOI: 10.1016/j.ejca.2010.06.117
Abstract: Inhibition of mTOR by rapamycin is an important approach in cancer therapy. In early clinical trials, tuberous sclerosis complex (TSC)-related kidney tumours were found to regress following ...
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Samy L. Habib,
Balakuntalam S. Kasinath,
Ruth Rector Arya,
Sandra Vexler,
Chakradhar Velagapudi
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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26 July 2010 |
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Health economics in drug development: Efficient research to inform healthcare funding decisions
DOI: 10.1016/j.ejca.2010.06.122
Abstract: In order to decide whether a new treatment should be used in patients, a robust estimate of efficacy and toxicity is no longer sufficient. As a result of increasing healthcare costs across t...
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Peter S. Hall,
Christopher McCabe,
Julia M. Brown,
David A. Cameron
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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26 July 2010 |
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Promoter polymorphisms in matrix metallopeptidase 1 and risk of cutaneous melanoma
DOI: 10.1016/j.ejca.2010.06.129
Abstract: Matrix metallopeptidase 1 (MMP1) is one of the interstitial collagens in the extracellular matrix metalloproteinase family and involved in tumour behaviours. However, there is no report on t...
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Li-E Wang,
Yu-jing Huang,
Ming Yin,
Jeffrey E. Gershenwald,
Victor G. Prieto,
Jeffrey E. Lee,
Madeleine Duvic,
Elizabeth A. Grimm,
Qingyi Wei
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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26 July 2010 |
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Protein kinase A-mediated phosphorylation of the RASSF1A tumour suppressor at Serine 203 and regulation of RASSF1A function
DOI: 10.1016/j.ejca.2010.06.128
Abstract: Epigenetic inactivation of the Ras-Association Domain Family 1A (RASSF1A) gene is one of the most frequent alterations detected in cancer. The tumour suppressor function of RASSF1A contribut...
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Antje M. Richter,
Undraga Schagdarsurengin,
Matthias Rastetter,
Katrin Steinmann,
Reinhard H. Dammann
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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26 July 2010 |
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Corrigendum to “Preclinical evidence for a beneficial impact of valproate on the response of small cell lung cancer to first-line chemotherapy” [Eur. J. Cancer 46(9) (2010) 1724-1734]
DOI: 10.1016/j.ejca.2010.06.120
The authors would like to draw your attention to the fact that the third author’s name should be listed as M. Cecilia Crisanti as stated above.
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Roland Hubaux,
Fabian Vandermeers,
M. Cecilia Crisanti,
Veena Kapoor,
Arsène Burny,
Céline Mascaux,
Steven M. Albelda,
Luc Willems
et al.
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European Journal of Cancer
Erratum
(In Press Corrected Proof)
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21 July 2010 |
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Cost-effectiveness of human papillomavirus vaccination and screening in Spain
DOI: 10.1016/j.ejca.2010.06.016
Abstract: Background: In Spain, prophylactic vaccination against human papillomavirus (HPV) types 16 and 18 is being offered free-of-charge to one birth cohort of girls aged 11–14. Screening is opport...
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Mireia Diaz,
Silvia de Sanjose,
Jesse Ortendahl,
Meredith O’Shea,
Sue J. Goldie,
F. Xavier Bosch,
Jane J. Kim
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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20 July 2010 |
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FGFR4 transmembrane domain polymorphism and cancer risk: A meta-analysis including 8555 subjects
DOI: 10.1016/j.ejca.2010.06.017
Abstract: Fibroblast growth factor receptor 4 (FGFR4), belonging to the receptor tyrosine kinase family, is involved in cancer initiation and progression. The FGFR4 Gly388Arg polymorphism in the trans...
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Wei Xu,
Yan Li,
Xueli Wang,
Bo Chen,
Yan Wang,
Shifeng Liu,
Jijun Xu,
Weihong Zhao,
Jianqing Wu
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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20 July 2010 |
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Double strand break repair components are frequent targets of microsatellite instability in endometrial cancer
DOI: 10.1016/j.ejca.2010.06.116
Abstract: Aim: DNA double strand break (DSB) repair is a central cellular mechanism of the DNA damage response to maintain genomic stability. DSB components are frequently mutated in colorectal cancer...
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Cristina Bilbao,
Raquel Ramírez,
Germán Rodríguez,
Orlando Falcón,
Laureano León,
Nicolás Díaz-Chico,
Manuel Perucho,
Juan Carlos Díaz-Chico
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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20 July 2010 |
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Determining research priorities for young people with haematological cancer: A value-weighting approach
DOI: 10.1016/j.ejca.2010.06.013
Abstract: Introduction: Haematological malignancies account for a third of all cancers affecting adolescents and young adults (AYAs). Funding agencies are regularly faced with the dilemma of how to de...
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Tara Clinton-McHarg,
Christine Paul,
Rob Sanson-Fisher,
Catherine D’Este,
Anna Williamson
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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15 July 2010 |
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Systematic review and meta-analysis of the discriminatory performance of risk prediction rules in febrile neutropaenic episodes in children and young people
DOI: 10.1016/j.ejca.2010.05.024
Abstract: Introduction: Febrile neutropaenia is a frequently occurring and occasionally life-threatening complication of treatment for childhood cancer, yet many children are aggressively over-treated...
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Bob Phillips,
Ros Wade,
Lesley A. Stewart,
Alex J. Sutton
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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12 July 2010 |
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Preoperative plasma TIMP-1 is an independent prognostic indicator in patients with primary colorectal cancer: A prospective validation study
DOI: 10.1016/j.ejca.2010.06.009
Abstract: Background: Previous studies have suggested plasma tissue inhibitor of metalloproteinases-1 (TIMP-1) as a stage independent prognostic marker in colorectal cancer (CRC) patients. The aim was...
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Helgi Birgisson,
Hans J. Nielsen,
Ib Jarle Christensen,
Bengt Glimelius,
Nils Brünner
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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09 July 2010 |
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Quality of life among long-term (⩾5 years) colorectal cancer survivors – Systematic review
DOI: 10.1016/j.ejca.2010.06.010
Abstract: Background: Due to the growing number of long-term (⩾5years) colorectal cancer survivors, investigation of their quality of life (QoL) is important for an evaluation of chronic or late effec...
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L. Jansen,
L. Koch,
H. Brenner,
V. Arndt
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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05 July 2010 |
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Is quantitative oestrogen receptor expression useful in the evaluation of the clinical prognosis? Analysis of a homogeneous series of 797 patients with prospective determination of the ER status using simultaneous EIA and IHC
DOI: 10.1016/j.ejca.2010.05.021
Abstract: Objective: Oestrogen receptor (ER) determination in breast cancer (BC) is a major yardstick for the prognosis and for response to hormonal therapy (HT). As several techniques have been propo...
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Chafika Mazouni,
Pascal Bonnier,
Aïcha Goubar,
Sylvie Romain,
Pierre-Marie Martin
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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05 July 2010 |
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Incidence of skin cancers during 5-year follow-up after stopping antioxidant vitamins and mineral supplementation
DOI: 10.1016/j.ejca.2010.06.008
Abstract: Context: In the SU.VI.MAX study, antioxidant supplementation for 7.5years was found to increase skin cancer risk in women but not in men. Objective: To investigate the potential residual or ...
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Khaled Ezzedine,
Julie Latreille,
Emmanuelle Kesse-Guyot,
Pilar Galan,
Serge Hercberg,
Christiane Guinot,
Denis Malvy
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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05 July 2010 |
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Prognostic impact of adenomatous polyposis coli gene expression in osteosarcoma of the extremities
DOI: 10.1016/j.ejca.2010.06.004
Abstract: Purpose: To evaluate the impact of adjuvant chemotherapy on the outcome of osteosarcoma of the extremities, and to identify prognostic factors using the expression of adenomatous polyposis c...
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Andréa Paiva Gadelha Guimarães,
Rafael Malagoli Rocha,
Isabela Werneck da Cunha,
Gustavo Cardoso Guimarães,
André Lopes Carvalho,
Beatriz de Camargo,
Ademar Lopes,
Jeremy Andrew Squire,
Fernando Augusto Soares
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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01 July 2010 |
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Anti-insulin-like growth factor 1 receptor antibody EM164 (murine AVE1642) exhibits anti-tumour activity alone and in combination with temozolomide against neuroblastoma
DOI: 10.1016/j.ejca.2010.06.005
Abstract: Insulin-like growth factor 1 receptor (IGF-1R) is overexpressed in many tumours and contributes to tumourigenicity, cell proliferation, metastasis and resistance, thus representing a promisi...
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Birgit Geoerger,
Jean-François Brasme,
Estelle Daudigeos-Dubus,
Paule Opolon,
Corinne Venot,
Laurent Debussche,
Patricia Vrignaud,
Gilles Vassal
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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30 June 2010 |
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Does socioeconomic status influence the prospect of cure from colon cancer – A population-based study in Sweden 1965–2000
DOI: 10.1016/j.ejca.2010.05.028
Abstract: Aim of study: Differences in the survival of colon cancer patients by socioeconomic status have been demonstrated in several populations, but the underlying reasons for the differences are n...
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S. Eloranta,
P.C. Lambert,
N. Cavalli-Bjorkman,
T.M.-L. Andersson,
B. Glimelius,
P.W. Dickman
et al.
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European Journal of Cancer
Full-length article
(In Press Corrected Proof)
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28 June 2010 |
