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The activation of an extracellular signal-regulated kinase by oestradiol interferes with the effects of trastuzumab on HER2 signalling in endometrial adenocarcinoma cell lines O. Treeck, K. Diedrich, O. Ortmann pages 1302-1309 Abstract | Full Text | Full-Text PDF (471 KB)
Differential expression of inducible nitric oxide synthase and peroxisome proliferator-activated receptor gamma in non-small cell lung carcinoma Tak W. Lee, George G. Chen, Hu Xu, Johnson H.Y. Yip, Ernest C.W. Chak, Tony S.K. Mok, Anthony P.C. Yim pages 1296-1301 Abstract | Full Text | Full-Text PDF (234 KB)
Review
Levels of absolute survival benefit for systemic therapies of advanced cancer: a call for standards J.P.A. Ioannidis, N. Pavlidis pages 1194-1198 Abstract | Full Text | Full-Text PDF (148 KB)
The level of physical activity in long-term survivors of testicular cancer L. Thorsen, W. Nystad, O. Dahl, O. Klepp, R.M Bremnes, E. Wist, S.D. Fosså pages 1216-1221 Abstract | Full Text | Full-Text PDF (206 KB)
Concurrent hypermethylation of gene promoters is associated with a MSI-H phenotype and diploidy in gastric carcinomas B Carvalho, M Pinto, L Cirnes, C Oliveira, J.C Machado, G Suriano, R Hamelin, F Carneiro, R Seruca pages 1222-1227 Abstract | Full Text | Full-Text PDF (211 KB)
Fulvestrant (Faslodex™) versus anastrozole for the second-line treatment of advanced breast cancer in subgroups of postmenopausal women with visceral and non-visceral metastases: combined results from two multicentre trials L. Mauriac, J.E. Pippen, J. Quaresma Albano, S.Z. Gertler, C.K. Osborne pages 1228-1233 Abstract | Full Text | Full-Text PDF (196 KB)
Thymidylate synthase inhibition triggers apoptosis via caspases-8 and -9 in both wild-type and mutant p53 colon cancer cell lines H.H.J Backus, D Wouters, C.G Ferreira, V.M.M van Houten, R.H Brakenhoff, H.M Pinedo, G.J Peters pages 1310-1317 Abstract | Full Text | Full-Text PDF (351 KB)
Trail-induced apoptosis and interaction with cytotoxic agents in soft tissue sarcoma cell lines S Tomek, W Koestler, P Horak, T Grunt, T Brodowicz, I Pribill, J Halaschek, G Haller, C Wiltschke, C.C Zielinski, M Krainer pages 1318-1329 Abstract | Full Text | Full-Text PDF (444 KB)
Prognostic significance of K-ras, p53, bcl-2, PCNA, CD34 in radically resected non-small cell lung cancers F Grossi, M Loprevite, M Chiaramondia, P Ceppa, C Pera, G.B Ratto, J Serrano, G.B Ferrara, R Costa, L Boni, A Ardizzoni pages 1242-1250 Abstract | Full Text | Full-Text PDF (216 KB)
Analysis of survival of mesothelioma cases in the Italian register (ReNaM) A Marinaccio, M Nesti, Regional Operational Centers pages 1290-1295 Abstract | Full Text | Full-Text PDF (154 KB)
Intrinsic variability in the detection of micrometastases in lymph nodes for re-staging of colorectal cancer: effect of individual markers and tissue samples M Salto-Tellez, S.L Kong, A.P.K Leong, E.S.C Koay pages 1234-1241 Abstract | Full Text | Full-Text PDF (213 KB)
Development of an EORTC disease-specific quality of life questionnaire for use in patients with liver metastases from colorectal cancer V. Kavadas, J.M. Blazeby, T. Conroy, O. Sezer, B. Holzner, M. Koller, J. Buckels, on behalf of the EORTC Quality of Life Group pages 1259-1263 Abstract | Full Text | Full-Text PDF (139 KB)
Temozolomide in patients with advanced non-small cell lung cancer with and without brain metastases: a phase II study of the EORTC Lung Cancer Group (08965) R Dziadziuszko, A Ardizzoni, P.E Postmus, E.F Smit, A Price, C Debruyne, C Legrand, G Giaccone, on behalf of the EORTC Lung Cancer Group pages 1271-1276 Abstract | Full Text | Full-Text PDF (145 KB)
Phase II trial with S-1 in chemotherapy-naı̈ve patients with gastric cancer. A trial performed by the EORTC Early Clinical Studies Group (ECSG) P Chollet, P Schöffski, K Weigang-Köhler, J.H.M Schellens, H Cure, N Pavlidis, V Grünwald, R De Boer, J Wanders, P Fumoleau pages 1264-1270 Abstract | Full Text | Full-Text PDF (238 KB)
An EORTC phase I study of capecitabine (Xeloda®) in combination with fixed doses of cyclophosphamide and epirubicin (cex) as primary treatment for large operable or locally advanced/inflammatory breast cancer H. Bonnefoi, L. Biganzoli, L. Mauriac, T. Cufer, P. Schaefer, G. Atalay, M. Piccart pages 1277-1283 Abstract | Full Text | Full-Text PDF (214 KB)
Oestrogen receptor beta (ERβ) is abundantly expressed in normal colonic mucosa, but declines in colon adenocarcinoma paralleling the tumour's dedifferentiation P.A Konstantinopoulos, A Kominea, G Vandoros, G.P Sykiotis, P Andricopoulos, I Varakis, G Sotiropoulou-Bonikou, A.G Papavassiliou pages 1251-1258 Abstract | Full Text | Full-Text PDF (456 KB)
Viridans streptococci bacteraemia in children with fever and neutropenia: a case–control study of predisposing factors H. Paganini, V Staffolani, P. Zubizarreta, L. Casimir, H. Lopardo, V. Luppino pages 1284-1289 Abstract | Full Text | Full-Text PDF (166 KB)
Genomics and proteomics in cancer J.P.A Baak, F.R.C Path, M.A.J.A Hermsen, G Meijer, J Schmidt, E.A.M Janssen pages 1199-1215 Abstract | Full Text | Full-Text PDF (934 KB)
Editorial Comment
Physical activity in long-term survivors of germ-cell cancer S. Sleijfer, R. de Wit pages 1191-1193 Full Text | Full-Text PDF (78 KB)
pages ix-x Full-Text PDF (65 KB)
pages 1185-1189 Full-Text PDF (147 KB)
Editorial board page ii Full-Text PDF (32 KB)
Calendar pages I-II Full-Text PDF (25 KB)
Announcement - Training Fellowships page III Full-Text PDF (114 KB)
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