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Information and communication in the context of a clinical trial
Abstract: The aim of this study was to determine the communicative needs of the patients in the context of being invited to participate in a clinical trial. A questionnaire was sent to 299 patients wi...
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P. Hietanen,
A.R. Aro,
K. Holli,
P. Absetz
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Full-length article
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pages 2096-2104
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Ovarian cancer: an institutional review of patterns of care, health insurance and prognosis
Abstract: The purpose of this study was to investigate the prognostic importance of the health insurance status in 145 consecutive patients with ovarian cancer diagnosed between 1984 and 1996. All pat...
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S Balli,
M.F Fey,
W Hänggi,
D Zwahlen,
G Berclaz,
E Dreher,
S Aebi
et al.
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Full-length article
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pages 2061-2068
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The attitudes of physicians and oncologists towards unconventional cancer therapies (UCT)
Abstract: Physicians represent the main providers of unconventional cancer therapies (UCT) in Germany. However, little is known about providers’ characteristics, as well as their attitudes towards UCT...
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K Münstedt,
A Entezami,
A Wartenberg,
U Kullmer
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Full-length article
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pages 2090-2095
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Selected micronutrients and colorectal cancer: a case–control study from the Canton of Vaud, Switzerland
Abstract: The association between dietary intake of various micronutrients and colorectal cancer risk was analysed using data from a case–control study conducted between 1992 and 1997 in the Swiss Can...
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F. Levi,
C. Pasche,
F. Lucchini,
C. La Vecchia
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Full-length article
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pages 2115-2119
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Germ line BRCA1 and BRCA2 gene mutations in Turkish breast cancer patients
Abstract: Germ line BRCA1 and/or BRCA2 mutations were screened in 50 Turkish breast and/or ovarian cancer patients composed of hereditary, familial, early onset and male cancer groups. Genomic DNA sam...
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H Özdag,
M Tez,
I Sayek,
M Müslümanoglu,
O Tarcan,
F Içli,
M Öztürk,
T Özçelik
et al.
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Full-length article
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pages 2076-2082
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Prognostic significance of TP53 gene mutation in 995 cases of colorectal carcinoma: influence of tumour site, stage, adjuvant chemotherapy and type of mutation
Abstract: Previous studies on the prognostic significance of TP53 gene alterations in colorectal cancer (CRC) have led to conflicting results. The present study investigated the prognostic significanc...
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R Soong,
B Powell,
H Elsaleh,
G Gnanasampanthan,
D.R Smith,
H.S Goh,
D Joseph,
B Iacopetta
et al.
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Full-length article
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pages 2053-2060
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A clinical nomogram for predicting long-term survival in advanced colorectal cancer
Abstract: From our prospectively accrued database of patients with gastrointestinal cancer, 1057 patients with advanced colorectal cancer were identified with the aim of determining predictive factors...
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C. Massacesi,
A. Norman,
T. Price,
M. Hill,
P. Ross,
D. Cunningham
et al.
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Full-length article
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pages 2044-2052
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BRCA1 mutations and clinicopathological features in a sample of Italian women with early-onset breast cancer
Abstract: Breast cancer in young women is uncommon and often presents with unfavourable biopathological features. Although early age at onset could suggest a genetic susceptibility to cancer, the appr...
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D Turchetti,
L Cortesi,
M Federico,
C Bertoni,
L Mangone,
Se Ferrari,
V Silingardi
et al.
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Full-length article
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pages 2083-2089
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Prospective evaluation of the contribution of K-ras mutational analysis and CA 19.9 measurement to cytological diagnosis in patients with clinical suspicion of pancreatic cancer
Abstract: The aim of this study was to prospectively evaluate the diagnostic contribution of the detection of K-ras mutation and measurement of serum CA 19.9 concentrations to cytological diagnosis in...
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E Urgell,
P Puig,
J Boadas,
G Capellà,
J.Ma Queraltó,
R Boluda,
A Antonijuan,
A Farré,
F Lluı́s,
F González-Sastre,
J Mora
et al.
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Full-length article
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pages 2069-2075
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Differential activity of topotecan, irinotecan and SN-38 in fresh human tumour cells but not in cell lines
Abstract: The topoisomerase I inhibitors topotecan irinotecan (CPT-11) and its metabolite SN-38 were studied in a panel of cell lines and in primary tumour cells from patients, using a non-clonogenic ...
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E Jonsson,
S Dhar,
B Jonsson,
P Nygren,
W Graf,
R Larsson
et al.
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Full-length article
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pages 2120-2127
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| Editorial Comment |
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Article Title |
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The art and science of prognosis in patients with advanced cancer
Prognosis has always held a fascination for humanity. Many of the earliest medical writings on Mesopotamian cuneiform tablets and Egyptian papyri are treatises about prognostication . From the Hippocr...
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D.P Steensma,
C.L Loprinzi
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Editorial
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pages 2025-2027
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Terminal cancer: duration and prediction of survival time
Abstract: The duration of the terminal period of cancer allows us to determine its prevalence, which is necessary to plan palliative care services. Clinical prediction of survival influences access to...
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J Llobera,
M Esteva,
J Rifà,
E Benito,
J Terrasa,
C Rojas,
O Pons,
G Catalán,
A Avellà
et al.
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Full-length article
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pages 2036-2043
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What does positron emission tomography offer oncology?
Abstract: The origins of positron emission tomography (PET) date back 70 years. Since the 1970s, however, its use has increased exponentially in the fields of neurology, cardiology and oncology. [18F]...
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H. Anderson,
P. Price
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Review article
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pages 2028-2035
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Family history of colorectal adenomatous polyps as a risk factor for colorectal cancer
Abstract: The aim of this study was to evaluate the risk of common colorectal cancer among first-degree relatives of patients with colorectal adenomatous polyps. In a population screening programme, 5...
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H Nakama,
B Zhang,
K Fukazawa,
A.S.M Abdul Fattah
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Full-length article
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pages 2111-2114
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Increased upstream methylation has no influence on the overexpression of the parathyroid hormone-related protein gene in squamous cell carcinoma of the lung
Abstract: Humoral hypercalcaemia of malignancy (HHM) commonly results from the excessive production of a parathyroid hormone-related protein (PTHrP) by tumours. We have previously shown malignancy is ...
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R.H Ganderton,
R.S.J Briggs
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Full-length article
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pages 2128-2136
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Attenuation of telomerase activity does not increase sensitivity of human melanoma cells to anticancer agents
Abstract: In tumour cells, replicative immortality is attained through stabilisation of telomeres by telomerase. Recent evidence suggests that telomerase plays an anti-apoptotic role. Since apoptosis ...
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M. Folini,
C. De Marco,
L. Orlandi,
M.G. Daidone,
N. Zaffaroni
et al.
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Full-length article
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pages 2137-2145
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Abundant expression of CD40 and CD40-ligand (CD154) in paediatric Langerhans cell histiocytosis lesions
Abstract: The pathogenesis of Langerhans cell histiocytosis (LCH) is obscure, partly because the events leading to activation of Langerhans-like lesional cells (LCH cells) and associated T cells, and ...
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R.M. Egeler,
B.E. Favara,
J.D. Laman,
E. Claassen
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Full-length article
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pages 2105-2110
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Gelatinolytic activity of matrix metalloproteinase-2 and -9 in oesophageal carcinoma; a study using in situ zymography
Abstract: In this study, we investigated the activity of matrix metalloproteinase (MMP)-2 and -9 by gelatine zymography, immunostaining and in situ gelatine zymography in 30 oesophageal squamous-cell ...
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H Koyama,
H Iwata,
Y Kuwabara,
H Iwase,
S Kobayashi,
Y Fujii
et al.
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Full-length article
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pages 2164-2170
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Cell cycle-related expression and ligand binding of peripheral benzodiazepine receptor in human breast cancer cell lines
Abstract: The aim of this study was to measure the expression of peripheral benzodiazepine receptors (PBR) as well as mitochondria content in different phases of the cell cycle of BT-20 and MCF-7 brea...
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N Sänger,
R Strohmeier,
M Kaufmann,
H Kuhl
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Full-length article
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pages 2157-2163
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Selection of cancer chemopreventive agents based on inhibition of topoisomerase II activity
Abstract: The present study was undertaken to determine if in vitro inhibition of one or both of the two most dominant mammalian DNA topoisomerases (topos) is common among chemopreventive agents. To d...
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K.H Cho,
J.M Pezzuto,
J.L Bolton,
V.E Steele,
G.J Kelloff,
S.K Lee,
A Constantinou
et al.
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Full-length article
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pages 2146-2156
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| Erratum |
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Erratum to ‘Imaging of cancer invasion and metastasis using green fluorescent protein’ Eur J Cancer 2000, 36(13), 1671–1680
It is regretted that the were printed as black and white. They are shown in colour below. We apologise for this mistake.
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J.S Candeelis,
J Wyckoff,
J.E Segall
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Erratum
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pages 2172-2173
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| Corrigendum |
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Article Title |
Author(s) |
Type |
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Immunohistochemical analysis of sporadic and familial (185delAG carriers) ovarian cancer in Israel
This paper by Ravid, et al., was published in Eur J Cancer 2000, 36(9), 1120–1124. It is regretted that Dr I. Barshack and Professor J. Kopolovic's names were spelt incorrectly in the original version...
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Erratum
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page 2171
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