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Author(s) |
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Alveolar soft part sarcoma: a report of 15 cases
Abstract: The aim of this study was to evaluate the presentation, course and treatment outcome of 15 patients with this rare type of sarcoma. The files of the patients were retrospectively analysed. O...
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S van Ruth,
F van Coevorden,
J.L Peterse,
B.B.R Kroon
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Full-length article
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pages 1324-1328
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| Review |
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Author(s) |
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Diagnostic advances and new trends for the treatment of primary central nervous system lymphoma
Abstract: Primary central nervous system lymphoma (PCNSL) is a rare non-Hodgkin's lymphoma arising in the brain. Recent increase in its incidence has been noted both in immunocompetent individuals and...
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U Basso,
A.A Brandes
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Full-length article
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pages 1298-1312
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High expression of DNA topoisomerase IIα and Ki-67 antigen is associated with prolonged survival in glioblastoma patients
Abstract: Assessment of tumour cell proliferation in glioblastoma (GB) has been a topic of considerable research interest over the past decade. However, the correlation of tumour proliferation and pat...
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Markus Bredel,
Maria Piribauer,
Christine Marosi,
Peter Birner,
Brigitte Gatterbauer,
Ingeborg Fischer,
Thomas Ströbel,
Karl Rössler,
Herbert Budka,
Johannes A. Hainfellner
et al.
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Full-length article
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pages 1343-1347
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Multicentre phase II and pharmacokinetic study of RFS2000 (9-nitro-camptothecin) administered orally 5 days a week in patients with glioblastoma multiforme
Abstract: A phase II trial was instigated to investigate the antitumour activity, the safety and the pharmacokinetic parameters of RFS2000, a recently identified oral topoisomerase I inhibitor, given ...
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E. Raymond,
M. Campone,
R. Stupp,
J. Menten,
P. Chollet,
T. Lesimple,
R. Fety-Deporte,
D. Lacombe,
X. Paoletti,
P. Fumoleau,
for the EORTC Early Clinical Studies Group (ECSG), Brain Tumour Studies Group (BTSG) and New Drug Development Program (NDDP), Brussels, Belgium
et al.
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Full-length article
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pages 1348-1350
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Factors influencing the prognostic role of oestrogen and progesterone receptor levels in breast cancer—results of the analysis of 670 patients with 11 years of follow-up
Abstract: In the last two decades, the prognostic role of the steroid hormone receptors has been the subject of a myriad of publications. Nevertheless, its relevance after long-term follow-up is still...
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S.-D Costa,
S Lange,
K Klinga,
E Merkle,
M Kaufmann
et al.
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Full-length article
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pages 1329-1334
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| Paediatric Update |
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Author(s) |
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Emergencies and their management
The prognosis for children with cancer has improved steadily over the last few decades so that overall approximately 70% will now be cured. Part of this improvement has been due to more effective trea...
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G Nicolin
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Short communication
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pages 1365-1377
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ErbB-4 expression in limb soft-tissue sarcoma: correlation with the results of neoadjuvant chemotherapy
Abstract: ErbB-4 is a recently described growth factor receptor. Relatively little is known about its expression in human tumours. In this study, we assessed the possible role of erbB-4 as a tissue ma...
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O. Merimsky,
J. Issakov,
J. Bickels,
Y. Kollender,
G. Flusser,
V. Soyfer,
I. Schwartz,
M. Inbar,
I. Meller
et al.
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Full-length article
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pages 1335-1342
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An evaluation of chest X-ray screening for lung cancer in gunma prefecture, Japan: a population-based case–control study
Abstract: In order to evaluate the efficacy of annual chest X-ray screening for lung cancer, a case–control study was conducted in Gunma Prefecture, Japan. Population-based annual lung cancer screenin...
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T Nakayama,
T Baba,
T Suzuki,
M Sagawa,
M Kaneko
et al.
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Full-length article
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pages 1380-1387
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The cellular pharmacology of oxaliplatin resistance
Abstract: Oxaliplatin is a third generation platinum compound that differs from cisplatin and carboplatin in having a broader spectrum of antitumour activity. Molecular studies suggest that oxaliplati...
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M Mishima,
G Samimi,
A Kondo,
X Lin,
S.B Howell
et al.
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Full-length article
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pages 1405-1412
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Baseline quality of life predicts survival in patients with advanced colorectal cancer
Abstract: The aim of this study was to investigate the influence of baseline quality of life (QoL) on survival in patients with advanced colorectal cancer. From 1992 to 1998, four randomised clinical ...
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N.R Maisey,
A Norman,
M Watson,
M.J Allen,
M.E Hill,
D Cunningham
et al.
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Full-length article
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pages 1351-1357
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| Review |
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Article Title |
Author(s) |
Type |
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Mind and cancer: do psychological factors cause cancer?
Abstract: We have reviewed the evidence for an association between major life events, depression and personality factors and the risk for cancer. We identified and included only those prospective or r...
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S.O Dalton,
E.H Boesen,
L Ross,
I.R Schapiro,
C Johansen
et al.
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Full-length article
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pages 1313-1323
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A randomised controlled study on the use of anti-inflammatory drugs in patients with cancer pain on morphine therapy: effects on dose-escalation and a pharmacoeconomic analysis
Abstract: The role of non-steroidal anti-inflammatory drugs (NSAIDs) in cancer pain has been well established in the treatment of mild pain and in association with opioids in the treatment of moderate...
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S Mercadante,
F Fulfaro,
A Casuccio
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Full-length article
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pages 1358-1363
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| Editorial Comment |
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Article Title |
Author(s) |
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Editorial comment on “In vitro toxicity of ET-743 and Aplidine, two marine-derived antineoplastics, on human bone marrow haematopoietic progenitors: comparison with the clinical results” by Albella and colleagues
In this issue of the European Journal of Cancer Albella and colleagues show that both ET-743 and Aplidine are toxic to human bone marrow cells, particularly megakaryocytic progenitors. For ET-743 the ...
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Maurizio D’Incalci
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Editorial
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page 1297
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Survival probabilities and hazard functions of malignant melanoma in Germany 1972–1996, an analysis of 10 433 patients. Evolution of gender differences and malignancy
Abstract: The evaluation of the impact of prevention activities on the course of survival in conjunction with the individual hazard rate of dying is described using data from a follow-up study of 10 4...
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K.F Kölmel,
B Kulle,
A Lippold,
C Seebacher
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Full-length article
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pages 1388-1394
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Commentary
This review of oncological emergencies offers an excellent account of the most common pitfalls in management of patients with malignant disease. Tumour lysis is a problem of newly diagnosed patients. ...
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S Lowis
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Discussion
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pages 1378-1379
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Vascular endothelial growth factor-C expression predicts lymph node metastasis of human gastric carcinomas invading the submucosa
Abstract: We examined the relationship between vascular endothelial growth factor (VEGF)-C expression and lymph node metastases in gastric carcinomas invading the submucosa. Of the six human gastric c...
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T Amioka,
Y Kitadai,
S Tanaka,
K Haruma,
M Yoshihara,
W Yasui,
K Chayama
et al.
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Full-length article
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pages 1413-1419
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News
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News
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pages 1291-1295
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In vitro toxicity of ET-743 and aplidine, two marine-derived antineoplastics, on human bone marrow haematopoietic progenitors: comparison with the clinical results
Abstract: Ecteinascidine-743 (ET-743) and aplidine are two marine-derived antineoplastics currently in phase II development. With the aim of evaluating whether in vitro haematopoietic studies can pred...
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B Albella,
G Faircloth,
L López-Lázaro,
C Guzmán,
J Jimeno,
J.A Bueren
et al.
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Full-length article
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pages 1395-1404
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Miscellaneous
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Miscellaneous
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pages vii-viii
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