| Parent Perspective |
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A journey through cancer—parental views, then and now
“At the beginning of 1980, our son Hamish was outwardly a healthy and fun loving boy of 5. By his sixth birthday in February of that year, although he still seemed well, he had occasionally complained...
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Antonya Cooper
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Short communication
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pages 2424-2426
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Neoadjuvant chemotherapy for locally advanced cervical cancer: a systematic review and meta-analysis of individual patient data from 21 randomised trials
Abstract: Despite the enrolment of more than 3000 women in randomised trials, the benefits and risks of neoadjuvant chemotherapy in the treatment of locally advanced cervical cancer remain uncertain. ...
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Neoadjuvant Chemotherapy for Cervical Cancer Meta-analysis Collaboration
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Full-length article
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pages 2470-2486
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| Letter |
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A comment on “Scandinavian Sarcoma Group Osteosarcoma Study SSG VIII: prognostic factors for outcome and the role of replacement salvage chemotherapy for poor histological responders”
We read with interest the paper of Smeland and colleagues about prognostic factors in 113 patients with osteosarcoma of the extremities treated in the last neoadjuvant study of the SSG. In their pape...
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G. Bacci,
A. Longhi,
C. Forni,
E. Setola,
E.S. Ferrari
et al.
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Correspondence
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page 2566
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| Editorial Comment |
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Neoadjuvant chemotherapy for locally advanced cervical cancer
The management of patients with locally advanced cancer of the uterine cervix remains a challenge, despite recent encouraging data. Historically, radiotherapy has been the standard treatment, with 5-y...
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E. Timotheadou,
M.E. Gore
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Editorial
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pages 2419-2421
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Cancer incidence and mortality in Portugal
Abstract: In this paper, we present estimates of national cancer incidence in Portugal in 1996–1998, predictions for the year 2000, and interpret the recent cancer mortality trends in light of observa...
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P.S. Pinheiro,
J.E. Tyczyński,
F. Bray,
J. Amado,
E. Matos,
D.M. Parkin
et al.
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Full-length article
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pages 2507-2520
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| Review |
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Size of invasive breast cancer and risk of local recurrence after breast-conservation therapy
Abstract: Risk of local recurrence is one important factor that determines a woman's suitability for breast-conservation therapy. With the evolution of oncoplastic surgery, tumours of a size that trad...
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K.S. Asgeirsson,
S.J. McCulley,
S.E. Pinder,
R.D. Macmillan
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Full-length article
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pages 2462-2469
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Clinical outcome of breast cancer patients with liver metastases alone in the anthracycline-taxane era: a retrospective analysis of two prospective, randomised metastatic breast cancer trials
Abstract: Liver metastases have long been known to indicate an unfavourable disease course in breast cancer (BC). However, a small subset of patients with liver metastases alone who were treated with ...
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G Atalay,
L Biganzoli,
F Renard,
R Paridaens,
T Cufer,
R Coleman,
A.H Calvert,
T Gamucci,
A Minisini,
P Therasse,
M.J Piccart,
on behalf of the EORTC Breast Cancer and Early Clinical Studies Groups
et al.
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Full-length article
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pages 2439-2449
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Allelic imbalance at loci containing FGFR, FGF, c-Met and HGF candidate genes in non-small cell lung cancer sub-types, implication for progression
Abstract: Fibroblast growth factors (FGF), hepatocyte growth factor (HGF) and their receptors, FGFR and c-Met, are essential components of the regulatory networks between the epithelium and mesenchyme...
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M. Beau-Faller,
M.P. Gaub,
A. Schneider,
E. Guérin,
Nicolas Meyer,
X. Ducrocq,
G. Massard,
B. Gasser,
R. Kessler,
E. Weitzenblum,
J.M. Wihlm,
E. Quoix,
P. Oudet
et al.
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Full-length article
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pages 2538-2547
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Trends in incidence of and mortality from cancer in The Netherlands in the period 1989–1998
Abstract: This paper summarises the population-based major trends in cancer incidence and mortality in the period 1989–1998 in The Netherlands. Trends of the European age-adjusted incidence and mortal...
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S. Siesling,
J.A.A.M. van Dijck,
O. Visser,
J.W.W. Coebergh,
on behalf of the Working Group of The Netherlands Cancer Registry
et al.
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Full-length article
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pages 2521-2530
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Mechanistic and anti-proliferative studies of two novel, biologically active bis-benzimidazoles
Abstract: We have previously synthesised a number of novel head-to-head bis-benzimidazole derivatives that are structurally related to the fluorochrome, Hoechst 33258, and which possess strong affinit...
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A Seaton,
C Higgins,
J Mann,
A Baron,
C Bailly,
S Neidle,
H van den Berg
et al.
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Full-length article
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pages 2548-2555
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| Review |
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Drug resistance reversal—are we getting closer?
Abstract: Clinical drug resistance is a major barrier to overcome before chemotherapy can become curative for most patients presenting with metastatic cancer. Rational attempts to tackle clinical drug...
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R.D Baird,
S.B Kaye
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Full-length article
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pages 2450-2461
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Are carcinomas of the cardia oesophageal or gastric adenocarcinomas?
Abstract: There is a clear relationship between Barrett's oesophagus and oesophageal adenocarcinoma, and between Helicobacter pylori and gastric cancer, but the histogenesis of cardiac adenocarcinomas...
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A Driessen,
D Van Raemdonck,
P De Leyn,
L Filez,
M Peeters,
V Winnepenninckx,
F Penninckx,
T Lerut,
N Ectors,
on behalf of the H.P. Belgian Contact Group
et al.
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Full-length article
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pages 2487-2494
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Routine radiography does not have a role in the diagnostic evaluation of ambulatory adult febrile neutropenic cancer patients
Abstract: Cancer patients treated with chemotherapy are susceptible to bacterial infections. When an adult patient presents with febrile neutropenia, standard diagnostic care includes physical examina...
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C.S.M Oude Nijhuis,
J.A Gietema,
E Vellenga,
S.M.G.J Daenen,
E.S.J.M De Bont,
W.A Kamps,
H.J.M Groen,
E.J van der Jagt,
W.T.A van der Graaf
et al.
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Full-length article
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pages 2495-2498
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| Corrigendum |
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Corrigendum to “An international field study of the reliability and validity of a disease-specific questionnaire module (the QLQ-OV28) in assessing the quality of life of patients with ovarian cancer” [European Journal of Cancer, 39 (2003) 1402–1408]☆
The corresponding author wishes to add M. Rios between B. Holzner and K. Kuljanic in the list of authors for the published paper mentioned above. The affiliation for M. Rios is Centre Alexis Vautrin, ...
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E. Greimel,
A. Bottomley,
A. Cull,
A.-C. Waldenstrom,
J. Arraras,
L. Chauvenet,
B. Holzner,
K. Kuljanic,
K. Lebrec,
S. D'haese,
on behalf of the EORTC Quality of Life Group and the Quality of Life Unit
et al.
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Erratum
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page 2570
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In vitro cytoprotective activity of squalene on a bone marrow versus neuroblastoma model of cisplatin-induced toxicity: implications in cancer chemotherapy
Abstract: The development of a non-toxic selective cytoprotective agent that preferentially protects normal tissues from chemotherapy toxicity, without protecting malignant tissues, is a major challen...
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B Das,
H Yeger,
H Baruchel,
M.H Freedman,
G Koren,
S Baruchel
et al.
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Full-length article
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pages 2556-2565
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Cytokine-regulated expression of collagenase-2 (MMP-8) is involved in the progression of ovarian cancer
Abstract: Matrix metalloproteinases (MMPs) have been implicated in ovarian cancer progression. Among them, MMP-8 that degrades type I collagen may play a crucial role. The aim of our study was to dete...
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S. Stadlmann,
J. Pollheimer,
P.L. Moser,
A. Raggi,
A. Amberger,
R. Margreiter,
F.A. Offner,
G. Mikuz,
S. Dirnhofer,
H. Moch
et al.
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Full-length article
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pages 2499-2505
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| Parent perspective |
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Author(s) |
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Childhood Cancer—a Mother's Story
In March 1994, when our son Stefan was 13 years of age, he was diagnosed with acute lymphoblastic leukaemia (ALL). He was treated with chemotherapy according to the BFM-92 protocol in the Children's U...
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Renate Pfeifer
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Short communication
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pages 2427-2429
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Association of genetic polymorphisms in CYP19 and CYP1A1 with the oestrogen receptor-positive breast cancer risk
Abstract: Since tamoxifen has been shown to reduce the risk of oestrogen receptor (ER)-positive, but not ER-negative, breast cancers in a chemoprevention trial (P-1), it is important to develop assays...
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Y Miyoshi,
A Ando,
S Hasegawa,
M Ishitobi,
J Yamamura,
N Irahara,
Y Tanji,
T Taguchi,
Y Tamaki,
S Noguchi
et al.
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Full-length article
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pages 2531-2537
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| Letter |
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Reply to comment on “Scandinavian Sarcoma Group Osteosarcoma Study SSG VIII: prognostic factors for outcome and the role of replacement salvage chemotherapy for poor histological responders”
The interesting letter by Bacci and colleagues published in this issue points out the prognostic impact of serum alkaline phosphatase (sALP) and serum lactate dehydrogenase (sLDH) in a recent analysis...
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S Smeland,
C Müller,
G Sæter
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Correspondence
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pages 2567-2568
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| Corrigendum |
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Corrigendum to “Elevated levels of circulating platelet microparticles, VEGF, IL-6 and RANTES in patients with gastric cancer: possible role of a metastasis predictor” [European Journal of Cancer, 39 (2003) 184-191]
The author regrets that the level unit of platelet microparticles was published incorrectly as “×109/ml” and should be corrected as follows “×106/ml”.
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H.K. Kim,
K.S. Song,
Y.S. Park,
Y.H. Kang,
Y.J. Lee,
K.R. Lee,
H.K. Kim,
K.W. Ryu,
J.M. Bae,
S. Kim
et al.
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Erratum
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page 2569
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| Position Paper |
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Continuing medical education and its accreditation—an overview of the situation in the European Union and in the United States
One of the aims of the Federation of European Cancer Societies (FECS) is to promote and harmonise the recognition of accreditation of continuing medical education (CME) in oncology in Europe. In order...
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K Vandendael,
F Van Hemelryck,
on behalf of the Federation of European Cancer Societies (FECS)
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Full-length article
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pages 2430-2438
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| Editorial Comment |
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Lessons from comparing CME Accreditation in Europe and the United States
The Position paper from the Federation of European Cancer Societies (FECS) on Continuing Medical Education (CME) accreditation that appears in this issue is timely and important. It clearly points out...
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Dennis K. Wentz
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Editorial
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pages 2422-2423
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Miscellaneous
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Miscellaneous
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pages ix-x
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News
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News
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pages 2413-2417
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Editorial Board
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Miscellaneous
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page ii
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Announcement
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Announcement
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page 2506
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Calendar
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Calendar
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pages I-II
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